Evidence map›Paper›PMID 37252093›Full record

ArticleRSC medicinal chemistry2023

Titanium complexes affect

Shahar Hayet, Mnar Ghrayeb, David N Azulay, Zohar Shpilt, Edit Y Tshuva, Liraz Chai

Open access · greenAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shahar HayetInstitute of Chemistry, The Hebrew University of Jerusalem Edmond J. Safra Campus Jerusalem 91904 Israel Edit.tshuva@mail.huji.ac.il Liraz.chai@mail.huji.ac.il +972 2 5660425 +972 2 6586084 +972 2 6585303.
Mnar GhrayebInstitute of Chemistry, The Hebrew University of Jerusalem Edmond J. Safra Campus Jerusalem 91904 Israel Edit.tshuva@mail.huji.ac.il Liraz.chai@mail.huji.ac.il +972 2 5660425 +972 2 6586084 +972 2 6585303.
David N AzulayInstitute of Chemistry, The Hebrew University of Jerusalem Edmond J. Safra Campus Jerusalem 91904 Israel Edit.tshuva@mail.huji.ac.il Liraz.chai@mail.huji.ac.il +972 2 5660425 +972 2 6586084 +972 2 6585303.ORCID https://orcid.org/0000-0002-6983-0446
Zohar ShpiltInstitute of Chemistry, The Hebrew University of Jerusalem Edmond J. Safra Campus Jerusalem 91904 Israel Edit.tshuva@mail.huji.ac.il Liraz.chai@mail.huji.ac.il +972 2 5660425 +972 2 6586084 +972 2 6585303.
Edit Y TshuvaInstitute of Chemistry, The Hebrew University of Jerusalem Edmond J. Safra Campus Jerusalem 91904 Israel Edit.tshuva@mail.huji.ac.il Liraz.chai@mail.huji.ac.il +972 2 5660425 +972 2 6586084 +972 2 6585303.
Liraz ChaiInstitute of Chemistry, The Hebrew University of Jerusalem Edmond J. Safra Campus Jerusalem 91904 Israel Edit.tshuva@mail.huji.ac.il Liraz.chai@mail.huji.ac.il +972 2 5660425 +972 2 6586084 +972 2 6585303.ORCID https://orcid.org/0000-0001-9644-4455
Hebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilms are surface or interface-associated communities of bacterial cells, embedded in a self-secreted extracellular matrix (ECM). Cells in biofilms are 100-1000 times more resistant to antibiotic treatment relative to planktonic cells due to various reasons, including the ECM acting as a diffusion barrier to antibiotic molecules, the presence of persister cells that divide slowly and are less susceptible to cell-wall targeting drugs, and the activation of efflux pumps in response to antibiotic stress. In this study we tested the effect of two titanium(iv) complexes that have been previously reported as potent and non-toxic anticancer chemotherapeutic agents on

Identifiers

PMID37252093
PMCPMC10211322
OpenAlexW4367663711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.