Evidence map›Paper›PMID 37252059›Full record

ArticleJournal of experimental pharmacology2023

Anthocyanin-Containing Purple Sweet Potato (

Eko Fuji Ariyanto, Widad Aghnia Shalannandia, Uci Ary Lantika, Taufik Muhammad Fakih, Dwi Syah Fitra Ramadhan, Arini Nurisydayanti Gumilar, Farhan Khalil Permana, Anisa Nadia Rahmah, Nur Atik, Astrid Feinisa Khairani

Open access · goldAbstract read
In one paragraph

Article in Journal of experimental pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Eko Fuji AriyantoDivision of Biochemistry and Molecular Biology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.ORCID 0000-0001-5161-4780
Widad Aghnia ShalannandiaDivision of Cell Biology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.ORCID 0000-0002-8182-1593
Uci Ary LantikaDepartment of Biomedical Sciences, Faculty of Medicine, Universitas Islam Bandung, Bandung, West Java, Indonesia.
Taufik Muhammad FakihDepartment of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, Bandung, West Java, Indonesia.ORCID 0000-0001-7155-4412
Dwi Syah Fitra RamadhanPoliteknik Kesehatan Kementerian Kesehatan Makassar, Makassar, Indonesia.
Arini Nurisydayanti GumilarUndergraduate Program Medical Doctor, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.
Farhan Khalil PermanaUndergraduate Program Medical Doctor, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.
Anisa Nadia RahmahUndergraduate Program Medical Doctor, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.
Nur AtikDivision of Cell Biology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.ORCID 0000-0001-5951-4733
Astrid Feinisa KhairaniDivision of Cell Biology, Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.ORCID 0000-0001-7242-4791
Padjadjaran University · IDBandung Islamic University · IDPoliteknik Kesehatan Kementerian Kesehatan Jakarta II · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We unravel the effect of anthocyanin-containing purple sweet potato synbiotic yogurt (PSPY) on 3T3-L1 adipocyte differentiation and its fundamental molecular mechanisms. Methods: Molecular docking simulation was performed to observe and identify the affinity and interaction between bioactive compounds and targeted proteins. MDI (isobutylmethylxanthine, dexamethasone, and insulin)-containing medium, a cocktail that stimulates adipogenesis, was used in this study. The toxic effect possibility of the yogurt product was evaluated using 3-[4, 5-dimethylthiazol-2-yl]-2.5 diphenyl tetrazolium bromide (MTT) assay. A 0.25%, 0.5%, 1%, and 5% (v/v) plain or purple sweet potato yogurt supernatant was given to 3T3-L1 preadipocyte culture medium from 24 h after seeding until day 11 of MDI-induced differentiation. The mRNA expression and lipid accumulation were analyzed using RT-qPCR and Oil red O staining, respectively, on day 11 after differentiation induction. Results: Conclusion: This study demonstrated PSPY inhibition effect on white adipocyte differentiation through suppression of

Indexed as

adipocyte differentiationanthocyaninPpargpurple sweet potato synbiotic yogurt

Identifiers

PMID37252059
PMCPMC10216850
OpenAlexW4377293107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.