ArticleFrontiers in pediatrics2023
The burden of congenital birth defects between 1990 and 2019 in China: an observational study.
Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Perinatal prevalence of birth defects in the Mainland of China, 2000-2021: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2024Pooled it
- Genetic testing and Guangdong college students in China: A cross-sectional study of knowledge and attitudes.Preventive medicine reports · 2025Article
- Emerging trends and cross-country health inequalities in congenital birth defects: insights from the GBD 2021 study.International journal for equity in health · 2025Article
- Down syndrome burden in China and globally: a comparative analysis of 1990-2021 trends and future projections based on GBD 2021 database.Frontiers in public health · 2025Article
- Analysis on the prevalence and temporal trends of adverse birth outcomes among neonates in Shanghai from 2010 to 2023.Frontiers in public health · 2025Article
- Role of genetics and the environment in the etiology of congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Review
- A Retrospective Cohort Study onInfection and drug resistance · 2024Article
- Prevalence, characteristics and risk factors of birth defects in central China livebirths, 2015-2022.Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Congenital birth defects (CBDs) are a major public health issue. This study aims to assess trends in the burden of CBDs between 1990 and 2019 across China based on the Global Burden of Disease Study 2019 (GBD 2019). Methods: Indicators of the burden of CBDs included incidence, mortality, and disability-adjusted life years (DALYs). Metrics included number, rate, and age-standardized rate with 95% uncertainty intervals (UIs). Data were stratified by region [China, global, high-, middle-, low-socio-demographic index (SDI)], age, sex, and type of CBD. Average annual percentage changes (AAPC) and trends were evaluated. Results: In China, between 1990 and 2019, the age-standardized incidence rate for CBDs showed an increasing trend, with an AAPC of 0.26% (0.11% to 0.41%), reaching 148.12 per 10 Conclusions: Morbidity associated with CBDs increased in China between 1990 and 2019, accelerated by the adoption of the two-child policy, and ranked high globally. These findings emphasize the need for prenatal screening and primary and secondary prevention strategies.
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