Evidence map›Paper›PMID 37251836›Full record

ArticleHeliyon2023

Seroprevalence of anti-SARS-CoV-2 antibodies and associated factors among household contacts of COVID-19 confirmed cases in Bangkok, Thailand.

Kamolthip Atsawawaranunt, Khammakorn Thiangthangthum, Somrak Sirikhetkon, Promporn Jampathong, Amornmas Kongklieng, Sutthichai Nakphook, Poolsap Phonsingh, Ritthideach Yorsaeng, Prabda Praphasiri, Anek Mungaomklang

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kamolthip AtsawawaranuntInstitute for Urban Disease Control and Prevention, Department of Disease Control, Ministry of Public Health, Thailand.
Khammakorn ThiangthangthumInstitute for Urban Disease Control and Prevention, Department of Disease Control, Ministry of Public Health, Thailand.
Somrak SirikhetkonInstitute for Urban Disease Control and Prevention, Department of Disease Control, Ministry of Public Health, Thailand.
Promporn JampathongInstitute for Urban Disease Control and Prevention, Department of Disease Control, Ministry of Public Health, Thailand.
Amornmas KongkliengThe Office of Disease Prevention and Control 6 Chonburi, Department of Disease Control, Ministry of Public Health, Thailand.
Sutthichai NakphookDivision of Epidemiology, Department of Disease Control, Ministry of Public Health, Thailand.
Poolsap PhonsinghThe Office of Disease Prevention and Control 8 Ubon Ratchathani, Department of Disease Control, Ministry of Public Health, Thailand.
Ritthideach YorsaengCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Thailand.
Prabda PraphasiriFaculty of Public Health, Kasetsart University, Sakon Nakhon, Thailand.
Anek MungaomklangThe Office of Disease Prevention and Control 4 Saraburi, Department of Disease Control, Ministry of Public Health, Thailand.
Ministry of Public Health · THChulalongkorn University · THKasetsart University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: High COVID-19 transmission among household (HH) contacts of infected cases were reported with seroprevalence varying from 5.5% to 57.2% worldwide. Data on seroprevalence among HH contacts and factors associated with seropositivity in Thailand are limited. Objectives: To determine the seroprevalence and factors associated with anti-SARS-CoV-2 antibodies among HH contacts of COVID-19 confirmed cases. Materials and methods: Data on confirmed COVID-19 cases (primary cases) in Bangkok from March 2020-July 2021 were retrieved from Institute for Urban Disease Control and Prevention. Primary cases were contacted within 14 days of testing positive for permission to contact their HH contacts via telephone. HH contacts were then recruited to complete questionnaires about demographics, and risk factors and blood was collected and tested for total immunoglobulin antibody against SARS-CoV-2 spike S1 protein. Factors associated with seropositivity were analysed by logistic regression. Results: Eligible participants of 452 HH contacts of infected cases in Bangkok were contacted. Seroprevalence was 20.5% among HH contacts. Factors associated with seropositivity after multivariate analysis were relationship to index case (being other relatives to index case (other than close relatives/spouse) [aOR 4.04, 95% CI; 1.15, 14.14, Conclusion: Serological investigation can be used in detecting COVID-19 infection in conjunction with other molecular techniques. It is a useful tool for studies on seroprevalence in a population as well as seroconversion after a vaccination campaign. Sharing living environments are associated with seropositivity in HH contacts. Nevertheless, individual practices can be affected by awareness, cultural differences, and control measures implemented by each country.

Indexed as

COVID-19Household contactSARS-CoV-2Seroprevalence

Identifiers

PMID37251836
PMCPMC10198736
OpenAlexW4377086847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.