Evidence map›Paper›PMID 37251813›Full record

ReviewThe World Allergy Organization journal2023

Comparison of allergen immunotherapy practice patterns in inhalant allergies in the United States of America and Europe: Similarities and differences 2023.

Oliver Pfaar, Sven Becker, Christopher Calabria, Diana Hartenstein, Jenna Jung, Julia Zimmer, Punita Ponda

Open access · goldAbstract readReview
In one paragraph

Review in The World Allergy Organization journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Patient perspectives of allergic rhinitis and allergen immunotherapy: A qualitative study.The journal of allergy and clinical immunology. Global · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Oliver PfaarDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Rhinology and Allergy, University Hospital Marburg, Philipps-Universität Marburg, Marburg.
Sven BeckerDepartment of Otorhinolaryngology, Head and Neck Surgery, Tübingen University Hospital, Germany.
Christopher CalabriaDepartment of Allergy and Immunology, Wilford Hall Medical Center, Lackland Air Force Base, San Antonio, TX, USA.
Diana HartensteinDivision of Allergology, Paul-Ehrlich-Institut, Langen, Germany.
Jenna JungDivision of Allergy and Immunology, Northwell Health, Great Neck, NY, USA.
Julia ZimmerDivision of Allergology, Paul-Ehrlich-Institut, Langen, Germany.
Punita PondaDivision of Allergy and Immunology, Northwell Health, Great Neck, NY, USA.
Northwell Health · USPaul Ehrlich Institut · DEPhilipps University of Marburg · DEUniversity Children's Hospital Tübingen · DEWilford Hall Ambulatory Surgical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgE-mediated atopic diseases such as allergic rhinitis and rhinoconjunctivitis are common chronic diseases in the western world. Allergen immunotherapy (AIT) plays a fundamental role in the treatment of allergic patients by modulating the underlying immune mechanisms. Though this treatment is integrated in practice-patterns globally, many differences are found in the application of AIT on the national or international level due to heterogeneous methods, and clinical recommendations are given in different parts of the world. This review from authors in Europe and the United States highlights differences and similarities in important aspects of AIT application in the 2 global regions. First, the regulatory situation differs regarding marketing authorization and licensing. Secondly, differences are elaborated in manufacturing practices, marketing distribution and formulations of AIT products. Thirdly, clinical administration patterns in the current guidelines show similarities in indications and contraindications of AIT, but also are divergent in some practical aspects. Informing the readership on similarities, as well as differences of standards in AIT in the United States and Europe, the authors highlight the unmet need of thorough harmonization of standards of AIT, as it is the only disease modifying treatment option available for patients with allergic rhinitis and rhinoconjunctivitis.

Indexed as

AITAllergen immunotherapyAllergic rhinitisEU dataHouse dust miteMedication scoreQuality of lifeSCITSLITSublingual immunotherapySymptom scoreTabletTotal combined rhinitis score

Identifiers

PMID37251813
PMCPMC10220280
OpenAlexW4377966373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.