Evidence map›Paper›PMID 37251726›Full record

ArticleJournal of orthopaedics2023

Current insights into the management of spinal cord injury.

Nisaharan Srikandarajah, Mohammed Ali Alvi, Michael G Fehlings

Open access · greenAbstract read
In one paragraph

Article in Journal of orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. AAD-2004 through clearing HScientific reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nisaharan SrikandarajahDivision of Neurosurgery and Spine Program, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Mohammed Ali AlviInstitute of Medical Science, University of Toronto, Toronto, ON, Canada.
Michael G FehlingsDivision of Neurosurgery and Spine Program, Department of Surgery, University of Toronto, Toronto, ON, Canada.
University of Toronto · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Traumatic spinal cord injury (SCI) is a serious disorder that results in severe impairment of neurological function as well as disability, ultimately reducing a patient's quality of life. The pathophysiology of SCI involves a primary and secondary phase, which causes neurological injury. Methods: Narrative review on current clinical management of spinal cord injury and emerging therapies. Results: This review explores the management of SCI through early decompressive surgery, optimizing mean arterial pressure, steroid therapy and focused rehabilitation. These management strategies reduce secondary injury mechanisms to prevent the propagation of further neurological damage. The literature regarding emerging research is also explored in cell-based, gene, pharmacological and neuromodulation therapies, which aim to repair the spinal cord following the primary injury mechanism. Conclusions: Outcomes for patients with SCI can be enhanced and improved if primary and secondary phases of SCI can be addressed.

Indexed as

BiomarkersHemodynamic managementNeuromodulationNeuroprotectionNeuroregenerationRehabilitationSpinal cord injurySurgical decompression

Identifiers

PMID37251726
PMCPMC10220467
OpenAlexW4376878742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.