ArticleFrontiers in endocrinology2023
Dose-response association of Chinese visceral adiposity index with comorbidity of hypertension and diabetes mellitus among elderly people.
Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Triglyceride-glucose index as a novel predictor of major adverse cardiovascular events in patients with coronary revascularization: a meta-analysis of cohort studies.Annals of medicine · 2026Pooled it
- Association Between Visceral Obesity Index and Diabetes: A Systematic Review and Meta-analysis.The Journal of clinical endocrinology and metabolism · 2024Pooled it
- Association of the TyG-related indices with hypertension-diabetes comorbidity in middle-aged and older adults: a suburban community-based study.BMC cardiovascular disorders · 2026Article
- Associations between multiple air pollutants and insulin resistance in Chinese adults: the moderating role of physical activity.BMC public health · 2026Article
- Cardiometabolic index is associated with hypertension among US older adults: An analysis of NHANES 2011-2018.Medicine · 2026Article
- Comparison of triglyceride-glucose related indices in prediction of cardiometabolic disease incidence among US midlife women.Scientific reports · 2025Observational
- A predictive nomogram for post-acute pancreatitis diabetes mellitus: a retrospective study.Archives of medical science : AMS · 2025Article
- Observational
- Association of the Triglyceride-Glucose Index and Obesity Indicators with Multiple Chronic Diseases: A Longitudinal Cohort Study Based on CHARLS.Journal of multidisciplinary healthcare · 2025Article
- Exploring the link between visceral fat and cardiovascular disease in type 2 diabetes: evidence from ct measurements.Frontiers in endocrinology · 2025Article
- Association of hypertension and long-term blood pressure changes with new-onset diabetes in the elderly: A 10-year cohort study.Diabetes, obesity & metabolism · 2025Article
- Association of heavy menstrual bleeding with cardiovascular disease in US female hospitalizations.BMC medicine · 2024Article
- Ideal cardiovascular health index and high-normal blood pressure in elderly people: evidence based on real-world data.Scientific reports · 2024Article
- The association between Chinese visceral adiposity index and cardiometabolic multimorbidity among Chinese middle-aged and older adults: a national cohort study.Frontiers in endocrinology · 2024Article
- Dose-response association between Chinese visceral adiposity index and cardiovascular disease: a national prospective cohort study.Frontiers in endocrinology · 2024Article
- Visceral adiposity as a predictor of new-onset diabetes in patients with primary aldosteronism: a cohort study.Therapeutic advances in chronic disease · 2024Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chinese visceral adiposity index (CVAI) is a reliable indicator of visceral obesity, but little is known about the association of CVAI with comorbidity of hypertension (HTN) and diabetes mellitus (DM). This study aimed to explore the associations of CVAI with HTN-DM comorbidity, HTN or DM, HTN, and DM in elderly people and evaluate the mediating role of insulin resistance in the associations. Methods: A total of 3,316 Chinese participants aged ≥60 years were included in this cross-sectional study. Logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Restricted cubic splines were applied to explore the dose-response associations. Mediation analyses were used to assess the mediating effect of triglyceride-glucose (TyG) index in the associations. Results: The prevalence rate of HTN-DM comorbidity, HTN or DM, HTN, and DM was 13.78%, 72.26%, 67.16%, and 18.88%, respectively. Linear associations between CVAI and HTN-DM comorbidity, HTN or DM, HTN, and DM were found, and ORs (95%CIs) were 1.45 (1.30-1.61), 1.39 (1.28-1.52), 1.36 (1.25-1.48), and 1.28 (1.16-1.41) for per SD increase in CVAI. Compared with quartile 1 of CVAI, the risk of HTN-DM comorbidity, HTN or DM, HTN, and DM increased 190%, 125%, 112%, and 96% for quartile 4. In addition, we found TyG index playing a key role in the associations of CVAI with HTN-DM comorbidity, HTN or DM, and DM. Conclusion: CVAI is linearly and positively correlated with HTN-DM comorbidity, HTN or DM, HTN, and DM. The potential mechanism is insulin resistance largely mediating the associations.
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