Evidence map›Paper›PMID 37251549›Full record

ArticleThe Egyptian journal of neurology, psychiatry and neurosurgery2023

Creutzfeldt-Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?

Taha K Alloush, Adel T Alloush, Yaser Abdelazeem, Hossam M Shokri, Khaled O Abdulghani, Ahmed Elzoghby

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Egyptian journal of neurology, psychiatry and neurosurgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Taha K AlloushDepartment of Neurology and Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Adel T AlloushDepartment of Geriatrics and Gerontology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Yaser AbdelazeemDepartement of Diagnostic Radiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Hossam M ShokriDepartment of Neurology and Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Khaled O AbdulghaniDepartment of Neurology and Psychiatry, Helwan University School of Medicine, Cairo, Egypt.ORCID 0000-0002-5700-9781
Ahmed ElzoghbyDepartement of Diagnostic Radiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Creutzfeldt-Jakob disease (CJD) is a rare, fatal neurodegenerative disorder, with few months as a usual duration from onset to death. Case presentation: In this case report, a patient of Sporadic CJD (sCJD) who presented one month after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The diagnosis of this case was established after confirming findings from clinical, neurophysiology, radiological, and laboratory features of this disease. Conclusion: Putting in mind all the updated data on the pathogenesis of CJD and the immune responses to SARS-CoV-2, we can suggest that COVID-19 can lead to accelerated pathogenesis and exaggerated manifestations of this fatal neurodegenerative disease.

Indexed as

COVID-19Neurodegenerative disorderPET/MRI brainSARS-CoV-2Sporadic Creutzfeldt–Jakob disease (sCJD)

Identifiers

PMID37251549
PMCPMC10201512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.