Evidence map›Paper›PMID 37251536›Full record

ArticleOpen medicine (Warsaw, Poland)2023

Identification of key enzalutamide-resistance-related genes in castration-resistant prostate cancer and verification of

Wen Xu, Li Liu, Zhongqi Cui, Mingyang Li, Jinliang Ni, Nan Huang, Yue Zhang, Jie Luo, Limei Sun, Fenyong Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wen XuShanghai Clinical College, Anhui Medical University, Shanghai, 200072, China.
Li LiuDepartment of Clinical Laboratory Medicine, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, China.
Zhongqi CuiDepartment of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.
Mingyang LiSchool of Life Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Jinliang NiShanghai Clinical College, Anhui Medical University, Shanghai, 200072, China.
Nan HuangDepartment of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.
Yue ZhangDepartment of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.
Jie LuoDepartment of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.
Limei SunDepartment of Clinical Laboratory, Shanghai Tenth People's Hospital of Tongji University, 200072, Shanghai, China.
Fenyong SunShanghai Clinical College, Anhui Medical University, No. 301, Yanchang Middle Road, Jingan District, Shanghai, 200072, China.
Tongji University · CNShanghai Medical College of Fudan University · CNJiangsu University · CNShanghai Children's Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with castration-resistant prostate cancer (CRPC) often develop drug resistance after treatment with enzalutamide. The goal of our study was to identify the key genes related to enzalutamide resistance in CRPC and to provide new gene targets for future research on improving the efficacy of enzalutamide. Differential expression genes (DEGs) associated with enzalutamide were obtained from the GSE151083 and GSE150807 datasets. We used R software, the DAVID database, protein-protein interaction networks, the Cytoscape program, and Gene Set Cancer Analysis for data analysis. The effect of

Indexed as

castration-resistant prostate cancerenzalutamideprostate cancerRAD51

Identifiers

PMID37251536
PMCPMC10224628
OpenAlexW4378472788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.