Evidence map›Paper›PMID 37251358›Full record

ArticleRespiratory medicine case reports2023

A case of development of autoimmune pulmonary alveolar proteinosis during the treatment of hypersensitivity pneumonitis.

Maki Asami-Noyama, Kosuke Ito, Misa Harada, Yukari Hisamoto, Yoshie Kunihiro, Eiji Ikeda, Tasuku Yamamoto, Junki Suizu, Ayumi Fukatsu, Syuichiro Ohata and 7 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Maki Asami-NoyamaDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Kosuke ItoDepartment of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
Misa HaradaDepartment of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
Yukari HisamotoDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Yoshie KunihiroDepartment of Radiology, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Eiji IkedaDepartment of Pathology, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Tasuku YamamotoDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Junki SuizuDepartment of Respiratory Medicine, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
Ayumi FukatsuDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Syuichiro OhataDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Yoriyuki MurataDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Keiji OishiDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Yoshikazu YamajiDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Nobutaka EdakuniDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Tomoyuki KakugawaDepartment of Pulmonology and Gerontology, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Tsunahiko HiranoDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Kazuto MatsunagaDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Yamaguchi University · JPNational Sanyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report the case of a 73-year-old woman with an occupational history of plaster grinding who developed autoimmune pulmonary alveolar proteinosis (PAP) during the treatment of fibrotic hypersensitivity pneumonitis with steroids and immunosuppressive drugs. Based on the changes in computed tomography imaging findings, poor response to steroid therapy, and markedly elevated KL-6 levels, PAP was suspected and diagnosed by bronchoscopy. Repeated segmental bronchoalveolar lavage under high-flow nasal cannula oxygen therapy resulted in slight improvement. Steroids and immunosuppressive treatments for other interstitial lung diseases may cause PAP or exacerbate latent PAP.

Indexed as

Anti-GM-CSF antibodyAutoimmune pulmonary alveolar proteinosisFibrotic hypersensitivity pneumoniaSegmental bronchoalveolar lavage

Identifiers

PMID37251358
PMCPMC10212751
OpenAlexW4376955824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.