Evidence map›Paper›PMID 37251008›Full record

ArticleInternational cancer conference journal2023

A long-term survival case of bladder cancer with distant metastases: abscopal effect of brain metastases after stereotactic radiotherapy with immune checkpoint blockade therapy to lung metastases.

Sawa Kono, Yaichiro Hashimoto, Yurie Shirai, Yasuhiro Kunihiro, Kenta Ohmatsu, Miki Kawanishi, Shigehiko Kuribayashi, Kumiko Karasawa

Open access · greenAbstract read
In one paragraph

Article in International cancer conference journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Who benefits from the abscopal effect?International cancer conference journal · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sawa KonoDepartment of Radiation Oncology, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.
Yaichiro HashimotoDepartment of Radiation Oncology, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.ORCID 0000-0001-5599-4530
Yurie ShiraiDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.
Yasuhiro KunihiroDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.
Kenta OhmatsuDepartment of Radiation Oncology, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.
Miki KawanishiDepartment of Radiation Oncology, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.
Shigehiko KuribayashiDepartment of Radiation Oncology, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.
Kumiko KarasawaDepartment of Radiation Oncology, Tokyo Women's Medical University School of Medicine, 8-1, Kawada-Cho, Shinjuku-Ku, Tokyo, 162-8666 Japan.
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain metastases from bladder cancer are rare, with a poor prognosis. There is no standard treatment for bladder cancer with brain metastases; thus, palliative therapy is generally provided. We report a case of abscopal effect in a single brain metastasis from bladder cancer in a patient treated with focal stereotactic radiotherapy (total dose = 52 Gy, administered in eight fractions) with immune checkpoint blockade therapy for lung metastases, who achieved long-term disease-free survival (> 4 years). To our knowledge, although there have been some reports on abscopal effects in bladder cancer, there are no previous reports on patients with brain metastases. To date, the brain metastasis, which showed an "abscopal effect," continues to maintain complete regression.

Indexed as

Abscopal effectBladder cancerBrain metastasesImmune checkpoint blockade therapyPembrolizumabStereotactic radiotherapy

Identifiers

PMID37251008
PMCPMC10212856
OpenAlexW4362580162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.