Evidence map›Paper›PMID 37250822›Full record

ArticleSAGE open medical case reports2023

Castleman's disease: A report of two cases at a tertiary hospital in Northern Tanzania.

Alex Mremi, Eliasa Ndale, Leonard Stephen, Elifuraha Mkwizu, Kajiru Kilonzo

Open access · goldAbstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alex MremiDepartment of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.ORCID https://orcid.org/0000-0001-7226-0168
Eliasa NdaleFaculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Leonard StephenDepartment of Internal Medicine, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Elifuraha MkwizuFaculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania.ORCID https://orcid.org/0000-0001-5938-5628
Kajiru KilonzoFaculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Kilimanjaro Christian Medical Centre · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Castleman's disease is a rare lympho-proliferative disease entity characterized by variable clinical presentations, distinctive histological manifestations, and prognosis. Its incidence and etiology are unclear. An interplay of HIV and human herpesvirus-8 has been implicated. Although its localized variety is benign, other types can be multifocal with adverse systemic manifestations. Human herpesvirus-8 Castleman's disease affects mainly HIV-positive individuals; however, individuals who are immunocompromised from other causes can also be affected, thus necessitating investigations for HIV. Herein, we report two patients presenting with long-standing lymphadenopathy. Histopathology, immunohistochemical testing and clinico-pathological correlation confirmed the diagnosis of Castleman's disease. The patients were successfully treated with surgery and/or rituximab. They were symptoms free in the subsequent follow-up visits. A brief review of the literature is also provided.

Indexed as

case reportCastleman’s diseaseTanzania

Identifiers

PMID37250822
PMCPMC10214097
OpenAlexW4378086235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.