Evidence map›Paper›PMID 37250769›Full record

ArticleiScience2023

DNA damage repair proteins across the Tree of Life.

Emily Nischwitz, Vivien A C Schoonenberg, Albert Fradera-Sola, Mario Dejung, Olga Vydzhak, Michal Levin, Brian Luke, Falk Butter, Marion Scheibe

Abstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. International journal of molecular sciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emily NischwitzInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Vivien A C SchoonenbergInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Albert Fradera-SolaInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Mario DejungInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Olga VydzhakInstitute of Developmental Biology and Neurobiology (IDN), Johannes-Gutenberg-University, 55128 Mainz, Germany.
Michal LevinInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Brian LukeInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Falk ButterInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.
Marion ScheibeInstitute of Molecular Biology (IMB), 55128 Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome maintenance is orchestrated by a highly regulated DNA damage response with specific DNA repair pathways. Here, we investigate the phylogenetic diversity in the recognition and repair of three well-established DNA lesions, primarily repaired by base excision repair (BER) and ribonucleotide excision repair (RER): (1) 8-oxoguanine, (2) abasic site, and (3) incorporated ribonucleotide in DNA in 11 species:

Indexed as

Evolutionary biologyMolecular biologyPhylogenetics

Identifiers

PMID37250769
PMCPMC10220248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.