Evidence map›Paper›PMID 37250489›Full record

ArticleTransplantation direct2023

Steroid Avoidance After Adult Living Donor Liver Transplant: A Cohort Analysis.

Miguel Nunez, Claudia R Praglin, Ana M Torres, Eliana Z Agudelo, Hillary J Braun, Chiung-Yu Huang, Shareef Syed, John P Roberts, Garrett R Roll

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplantation direct, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Miguel NunezSchool of Medicine, University of California San Francisco, San Francisco, CA.
Claudia R PraglinDivision of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
Ana M TorresDivision of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
Eliana Z AgudeloDivision of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
Hillary J BraunDepartment of Surgery, University of California San Francisco, San Francisco, CA.
Chiung-Yu HuangDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA.
Shareef SyedDivision of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
John P RobertsDivision of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
Garrett R RollDivision of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA.
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although steroid avoidance (SA) has been studied in deceased donor liver transplant, little is known about SA in living donor liver transplant (LDLT). We report the characteristics and outcomes, including the incidence of early acute rejection (AR) and complications of steroid use, in 2 cohorts of LDLT recipients. Methods: Routine steroid maintenance (SM) after LDLT was stopped in December 2017. Our single-center retrospective cohort study spans 2 eras. Two hundred forty-two adult recipients underwent LDLT with SM (January 2000-December 2017), and 83 adult recipients (December 2017-August 2021) underwent LDLT with SA. Early AR was defined as a biopsy showing pathologic characteristics within 6 mo after LDLT. Univariate and multivariate logistic regressions were performed to evaluate the effects of relevant recipient and donor characteristics on the incidence of early AR in our cohort. Results: Neither the difference in early AR rate between cohorts (SA 19/83 [22.9%] versus SM 41/242 [17%]; Conclusions: LDLT recipients treated with SA do not exhibit significantly higher rates of rejection or increased mortality than patients treated with SM. Notably, this result is similar for recipients with autoimmune disease.

Identifiers

PMID37250489
PMCPMC10212610
OpenAlexW4378071207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.