Evidence map›Paper›PMID 37250410›Full record

ArticleFrontiers in neuroscience2023

Intranasal 15d-PGJ2 inhibits the growth of rat lactotroph pituitary neuroendocrine tumors by inducing PPARγ-dependent apoptotic and autophagic cell death.

Zongyang Li, Lei Chen, Di Zhang, Xianjian Huang, Jihu Yang, Weiping Li, Chuanfang Wang, Xiangbao Meng, Guodong Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zongyang LiDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Lei ChenDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Di ZhangDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Xianjian HuangDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Jihu YangDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Weiping LiDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Chuanfang WangDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Xiangbao MengDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Guodong HuangDepartment of Neurosurgery, Shenzhen Second People's Hospital, School of Pharmaceutial Science, Health Science Center, Shenzhen University, Shenzhen, China.
Shenzhen Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PPARγ agonists have been reported to induce cell death in pituitary neuroendocrine tumor (PitNET) cell cultures. However, the therapeutic effects of PPARγ agonists

Indexed as

15d-PGJ2apoptosisautophagypituitary neuroendocrine tumorsPPARγ

Identifiers

PMID37250410
PMCPMC10213263
OpenAlexW4376280116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.