Evidence map›Paper›PMID 37250379›Full record

ArticleIDCases2023

Gastrointestinal basidiobolomycosis - A rare fungal infection: Challenging to diagnose yet treatable - Case report and literature review.

Saeed Mirmoosavi, Mohammadreza Salehi, Reza Fatahi, Amanuel Godana Arero, Hasti Kamali Sarvestani, Farid Azmoudeh-Ardalan, Faeze Salahshour, Masoomeh Safaei, Sara Ghaderkhani, Foroogh Alborzi Avanaki

Open access · goldAbstract readCase Reports
In one paragraph

Article in IDCases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Saeed MirmoosaviEndocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Mohammadreza SalehiResearch Center for Antibiotic Stewardship & Antimicrobial Resistance, Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Reza FatahiResearch Center for Antibiotic Stewardship & Antimicrobial Resistance, Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Amanuel Godana AreroCardiac Primary Prevention Research Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Hasti Kamali SarvestaniDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Farid Azmoudeh-ArdalanImam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Faeze SalahshourAdvance Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Masoomeh SafaeiDepartment of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Sara GhaderkhaniDepartment of Infectious Diseases, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Foroogh Alborzi AvanakiImam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Tehran University of Medical Sciences · IRImam Khomeini Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal Basidiobolomycosis is a rare manifestation of Basidiobolus ranarum infection. In this report, we present two cases of gastrointestinal Basidiobolomycosis. The first patient presented with obstructive symptoms, fever, and weight loss. The diagnosis of Basidiobolomycosis was not made until after surgery, when Liposomal amphotericin-B combined with itraconazole were administered, leading to the resolution of laboratory markers of inflammation and patient's symptoms. The second case involves a young woman who presented with hematochezia, perianal induration, and abdominal pain. The patient had previously been diagnosed with Crohn's disease and treated accordingly, but her symptoms did not improve. Due to the endemicity of tuberculosis in Iran, the patient was treated for TB but still showed no improvement. However, a perianal biopsy sample revealed the Splendore Hoeppli phenomenon and fungal elements in GMS staining, leading to the diagnosis of gastrointestinal Basidiobolomycosis. Treatment with itraconazole and co-trimoxazole led to a significant improvement in symptoms and laboratory indices after one week, including the resolution of perianal induration. The key takeaway from this report is the importance of considering rare infections in the differential diagnosis of gastrointestinal conditions such as IBD and GI obstruction.

Indexed as

BasidiobolomycosisCrohn’s diseaseFungal infectionGastrointestinal basidiobolomycosisGastrointestinal obstructionInflammatory bowel disease

Identifiers

PMID37250379
PMCPMC10220263
OpenAlexW4377194612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.