Evidence map›Paper›PMID 37250266›Full record

ArticleJournal of anaesthesiology, clinical pharmacology

Effects of adding dexmedetomidine to nebulized lidocaine on control of hemodynamic responses to laryngoscopy and intubation: A randomized clinical trial.

Bhavna Sriramka, Zeeshan Haider Warsi, Janmejaya Sahoo

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05941767 nacompletednot on this map

Comparing Intravenous Versus Nebulized Either Lidocaine or Dexmedetomidine for Attenuation of the Hemodynamic Responses to Laryngoscopy and Intubation

TypeinterventionalSponsorZagazig UniversityRan2023 to 2024Enrolled100ConditionsAnesthesia Intubation ComplicationArmsDexmedetomidine nebulization, Lidocaine nebulization, Dexmedetomidine IV, Lidocaine IV
NCT06254534 naunknown statusnot on this map

Effect of Lidocaine, Dexmedetomidine, Esmolol and Magnesium Use on Optic Nerve Sheath Diameter and Hemodynamic Response After Laryngoscopy: Randomized, Controlled, Double-blind Trial

TypeinterventionalSponsorHaseki Training and Research HospitalRan2024 to 2025Enrolled100ConditionsIntracranial Hypertension, Endotracheal Intubation, Optic Nerve Sheath Diameter, General AnesthesiaArmsoptic nerve ultrasonography
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Bhavna SriramkaDepartment of Anesthesia and Critical Care, IMS and Sum Hospital, Bhubaneswar, Odisha, India.
Zeeshan Haider WarsiDepartment of Anesthesia and Critical Care, IMS and Sum Hospital, Bhubaneswar, Odisha, India.
Janmejaya SahooDepartment of Anesthesia and Critical Care, IMS and Sum Hospital, Bhubaneswar, Odisha, India.
Institute of Medical Sciences and Sum Hospital · INCreative Commons · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Hemodynamic responses (HDR) to laryngoscopy and intubation are a significant concern for the anesthesiologist. This study aimed to compare the effects of intravenous Dexmedetomidine and nebulized Lidocaine for control of HDR to laryngoscopy and intubation when used in combination or alone. Material and Methods: This double-blind, parallel group, randomized clinical trial included 90 patients (30 for each group) aged 18-55 years with ASA grade 1-2. Group DL received intravenous (IV) Dexmedetomidine (1 μg kg Results: Post-intubation HR was better controlled in group DL than group D and group L (76.40 ± 5.61, 95.16 ± 10.60, 103.90 ± 12.98 respectively, Conclusion: We found the addition of intravenous Dexmedetomidine to nebulized Lidocaine to be superior in controlling the increase in HR and MBP post-intubation with no adverse effects.

Indexed as

Blood pressuredexmedetomidineheart rateintratrachealintubationlaryngoscopylidocaine

Identifiers

PMID37250266
PMCPMC10220189
OpenAlexW4327884534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.