Evidence map›Paper›PMID 37250072›Full record

ArticleFrontiers in public health2023

Transmission of

Ying Lin, Yuhua Du, Hongcheng Shen, Yangfeng Guo, Ting Wang, Keng Lai, Danni Zhang, Guangmin Zheng, Guifeng Wu, Yu Lei and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ying Lin *Department of Tuberculosis Control, Guangzhou Chest Hospital, Guangzhou, China.
Yuhua Du *Department of Tuberculosis Control, Guangzhou Chest Hospital, Guangzhou, China.
Hongcheng ShenDepartment of Preventive Health Care, Guangzhou Chest Hospital, Guangzhou, China.
Yangfeng GuoGuangzhou Primary and Secondary School Health and Health Promotion Center, Guangzhou, China.
Ting WangDepartment of Tuberculosis Control, Guangzhou Chest Hospital, Guangzhou, China.
Keng LaiDepartment of Tuberculosis Control, Guangzhou Chest Hospital, Guangzhou, China.
Danni ZhangAcademy of Public Health, Guangzhou Medical University, Guangzhou, China.
Guangmin ZhengAcademy of Public Health, Guangzhou Medical University, Guangzhou, China.
Guifeng WuDepartment of Tuberculosis Control, Guangzhou Chest Hospital, Guangzhou, China.
Yu LeiDepartment of Tuberculosis Control, Guangzhou Chest Hospital, Guangzhou, China.
Jianxiong LiuDepartment of Tuberculosis Control, Guangzhou Chest Hospital, Guangzhou, China.
Guangzhou Chest Hospital · CNGuangzhou Medical University · CNGuangzhou Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: China is a country with a high burden of tuberculosis (TB). TB outbreaks are frequent in schools. Thus, understanding the transmission patterns is crucial for controlling TB. Method: In this genomic epidemiological study, the conventional epidemiological survey data combined with whole-genome sequencing was used to assess the genotypic distribution and transmission characteristics of Result: The TB incidence was mainly concentrated in regular secondary schools and technical and vocational schools. The incidence of drug resistance among the students was 16.30% (22/135). The phylogenetic tree showed that 79.26% (107/135) and 20.74% (28/135) of the strains belonged to lineage 2 (Beijing genotype) and lineage 4 (Euro-American genotype), respectively. Among the 135 isolates, five clusters with genomic distance within 12 single nucleotide polymorphisms were identified; these clusters included 10 strains, accounting for an overall clustering rate of 7.4% (10/135), which showed a much lower transmission index. The distance between the home or school address and the interval time of symptom onset or diagnosis indicated that campus dissemination and community dissemination may be existed both, and community dissemination is the main. Conclusion and recommendation: TB cases in Guangzhou schools were mainly disseminated and predominantly originated from community transmission. Accordingly, surveillance needs to be strengthened to stop the spread of TB in schools.

Indexed as

Mycobacterium tuberculosisTuberculosisTuberculosis, Multidrug-ResistantChinaHumansPhylogenycluster analysisepidemiological studymultidrug-resistant Mycobacterium tuberculosisphylogenetic analysisschoolwhole-genome sequencing

Identifiers

PMID37250072
PMCPMC10219607
OpenAlexW4376279402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.