Evidence map›Paper›PMID 37249708›Full record

ReviewCell and tissue research2023

miRNAs contributing to the repair of tendon injury.

Kexin Lyu, Xinyue Liu, Tianzhu Liu, Jingwei Lu, Li Jiang, Yixuan Chen, Longhai Long, Xiaoqiang Wang, Houyin Shi, Fan Wang and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell and tissue research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kexin Lyu *School of Physical Education, Southwest Medical University, Luzhou, China.
Xinyue Liu *School of Physical Education, Southwest Medical University, Luzhou, China.
Tianzhu Liu *Neurology Department, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Jingwei LuSchool of Physical Education, Southwest Medical University, Luzhou, China.
Li JiangSchool of Physical Education, Southwest Medical University, Luzhou, China.
Yixuan ChenSchool of Physical Education, Southwest Medical University, Luzhou, China.
Longhai LongSpinal Surgery Department, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Xiaoqiang WangSpinal Surgery Department, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Houyin ShiTraumatology and Orthopedics Department, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Fan WangThe Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Sen LiSpinal Surgery Department, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China. jht187@163.com.ORCID http://orcid.org/0000-0002-4819-097X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tendon injury is one of the most common disorders of the musculoskeletal system, with a higher likelihood of occurrence in elderly individuals and athletes. In posthealing tendons, two undesirable consequences, tissue fibrosis and a reduction in mechanical properties, usually occur, resulting in an increased probability of rerupture or reinjury; thus, it is necessary to propose an appropriate treatment. Currently, most methods do not sufficiently modulate the tendon healing process and restore the function and structure of the injured tendon to those of a normal tendon, since there is still inadequate information about the effects of multiple cellular and other relevant signaling pathways on tendon healing and how the expression of their components is regulated. microRNAs are vital targets for promoting tendon repair and can modulate the expression of biological components in signaling pathways involved in various physiological and pathological responses. miRNAs are a type of noncoding ribonucleic acid essential for regulating processes such as cell proliferation, differentiation, migration and apoptosis; inflammatory responses; vascularization; fibrosis; and tissue repair. This article focuses on the biogenesis response of miRNAs while presenting their mechanisms in tendon healing with perspectives and suggestions.

Indexed as

MicroRNAsTendon InjuriesAgedCell DifferentiationFibrosisHumansTendonsMicroRNAsmiRNAsTendonTendon healingTendon injuryTendon repair

Identifiers

PMID37249708
PMCPMC10406718

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.