Evidence map›Paper›PMID 37249612›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2023

Antimicrobial peptides as potential therapy for gastrointestinal cancers.

Xiaoxia Yang, Cui Hua, Lin Lin, Zhao Ganting

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xiaoxia YangHeping Hospital Attached to Changzhi Medical College, Changzhi, 046000, China.
Cui HuaTangshan Fengnan District Traditional Chinese Medicine Hospital, Tangshan, 063000, China. CuiHua660@gmail.com.
Lin LinTangshan Hongci Hospital, Tangshan, 063000, China.
Zhao GantingHeping Hospital Attached to Changzhi Medical College, Changzhi, 046000, China.
Changzhi Medical College · CNTangshan People's Hospital · CNTraditional Chinese Medicine Hospital of Kunshan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since conventional therapy faces limitations in the field of different cancers as well as gastrointestinal cancers, that decrease the survival rate of patients, there is an urgent need to find new effective therapeutic approaches without the adverse effects of the traditional agents. Antimicrobial peptides (AMPs) attract much attention and are well known for their role in innate immunity. These peptides, in addition to their antimicrobial activity, exhibit strong anticancer potential against various types of malignancy. AMPs specifically target tumor cells and have selective toxicity for these cells without affecting normal cells. Here we aim to comprehensively overview the current knowledge in the field of using AMPs as novel therapeutic agents for gastrointestinal cancer.

Indexed as

Antimicrobial Cationic PeptidesGastrointestinal NeoplasmsAntimicrobial PeptidesHumansAntimicrobial Cationic PeptidesAntimicrobial PeptidesAngiogenesisAntimicrobial peptides (AMPs)ApoptosisGastrointestinal cancerTherapeutics

Identifiers

PMID37249612
OpenAlexW4378746576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.