Evidence map›Paper›PMID 37249316›Full record

ArticleHuman vaccines & immunotherapeutics2023

Temporal trends and determinants of COVID-19 vaccine series initiation after recent pregnancy.

Eszter Török, Tavleen Dhinsa, Sheryll Dimanlig-Cruz, Gillian D Alton, Ann E Sprague, Sandra I Dunn, Prakesh S Shah, Darine El-Chaâr, Annette K Regan, Kumanan Wilson and 10 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. SARS-CoV-2, Tdap, and influenza vaccination during pregnancy from 2019 to 2022 in Ontario, Canada: a population-based retrospective cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Eszter TörökChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Tavleen DhinsaBetter Outcomes Registry and Network (BORN) Ontario, Ottawa, ON, Canada.
Sheryll Dimanlig-CruzBetter Outcomes Registry and Network (BORN) Ontario, Ottawa, ON, Canada.
Gillian D AltonChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Ann E SpragueChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Sandra I DunnBetter Outcomes Registry and Network (BORN) Ontario, Ottawa, ON, Canada.
Prakesh S ShahDepartment of Paediatrics, Mount Sinai Hospital, Toronto, ON, Canada.
Darine El-ChaârSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Annette K ReganSchool of Nursing and Health Professions, University of San Francisco, San Francisco, CA, USA.
Kumanan WilsonClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.ORCID 0000-0002-1741-7705
Sarah A BuchanPublic Health Ontario, Toronto, ON, Canada.
Jeffrey C KwongPublic Health Ontario, Toronto, ON, Canada.
Siri E HåbergCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Christopher A GravelSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Nannette OkunDepartment of Obstetrics and Gynaecology, University of Toronto, Toronto, ON, Canada.
Mark C WalkerChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.
Shannon E MacDonaldFaculty of Nursing, University of Alberta, Edmonton, AB, Canada.
Sarah E WilsonPublic Health Ontario, Toronto, ON, Canada.
Jon BarrettDepartment of Obstetrics and Gynaecology, McMaster University, Hamilton, ON, Canada.
Deshayne B FellChildren's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the rapid deployment of COVID-19 vaccines in 2021, safety concerns may have led some pregnant individuals to postpone vaccination until after giving birth. This study aimed to describe temporal patterns and factors associated with COVID-19 vaccine series initiation after recent pregnancy in Ontario, Canada. Using the provincial birth registry linked with the COVID-19 vaccine database, we identified all individuals who gave birth between January 1 and December 31, 2021, and had not yet been vaccinated by the end of pregnancy, and followed them to June 30, 2022 (follow-up ranged from 6 to 18 months). We used cumulative incidence curves to describe COVID-19 vaccine initiation after pregnancy and assessed associations with sociodemographic, pregnancy-related, and health behavioral factors using Cox proportional hazards regression to estimate adjusted hazard ratios (aHR) and 95% confidence intervals (CI). Among 137,198 individuals who gave birth in 2021, 87,376 (63.7%) remained unvaccinated at the end of pregnancy; of these, 65.0% initiated COVID-19 vaccination by June 30, 2022. Lower maternal age (<25 vs. 30-34 y aHR: 0.73, 95%CI: 0.70-0.77), smoking during pregnancy (vs. nonsmoking aHR: 0.68, 95%CI: 0.65-0.72), lower neighborhood income (lowest quintile vs. highest aHR: 0.79, 95%CI: 0.76-0.83), higher material deprivation (highest quintile vs. lowest aHR: 0.74, 95%CI: 0.70-0.79), and exclusive breastfeeding (vs. other feeding aHR: 0.81, 95%CI: 0.79-0.84) were associated with lower likelihood of vaccine initiation. Among unvaccinated individuals who gave birth in 2021, COVID-19 vaccine initiation after pregnancy reached 65% by June 30, 2022, suggesting persistent issues with vaccine hesitancy and/or access to vaccination in this population.

Indexed as

COVID-19COVID-19 VaccinesCognitionDatabases, FactualFemaleHumansOntarioPregnancyVaccinationCOVID-19 VaccinesbirthCOVID-19COVID-19 vaccinationCOVID-19 vaccine series initiationpregnancypregnant

Identifiers

PMID37249316
PMCPMC10305504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.