Evidence map›Paper›PMID 37249312›Full record

ArticleJournal of dental research2023

Autophagy Plays a Crucial Role in Ameloblast Differentiation.

C Iwaya, A Suzuki, J Shim, C G Ambrose, J Iwata

Open access · hybridAbstract read
In one paragraph

Article in Journal of dental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Roles of calcium in ameloblasts during tooth development: A scoping review.Journal of Taibah University Medical Sciences · 2025
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

C IwayaDepartment of Diagnostic & Biomedical Sciences, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX, USA.
A SuzukiDepartment of Diagnostic & Biomedical Sciences, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX, USA.ORCID 0000-0003-3163-8093
J ShimDepartment of Diagnostic & Biomedical Sciences, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX, USA.
C G AmbroseDepartment of Orthopedic Surgery at McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
J IwataDepartment of Diagnostic & Biomedical Sciences, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX, USA.ORCID 0000-0003-3975-6836
The University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Role of cellular metabolism in palate morphogenesisR01DE029818 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI, ZHAO, ZHONGMING · 2020 to 2024
$1.8M
Molecular Regulatory Mechanism of Calvaria Bone Development and HomeostasisR01DE026767 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2017 to 2021
$1.8M
NIDCR NIH HHS R01 DE026767NIDCR NIH HHS R01 DE029818
6 · The paper itself

Abstract

Tooth enamel is generated by ameloblasts. Any failure in amelogenesis results in defects in the enamel, a condition known as amelogenesis imperfecta. Here, we report that mice with deficient autophagy in epithelial-derived tissues (

Indexed as

AmeloblastsAmelogenesis ImperfectaAmelogenesisAnimalsMiceMice, KnockoutNF-E2-Related Factor 2Repressor ProteinsTumor Suppressor ProteinsX-Ray MicrotomographyBcl11b protein, mouseNF-E2-Related Factor 2Repressor ProteinsTumor Suppressor Proteinsameloblastsamelogenesis imperfectaAtg3Atg7enamel formationtooth development

Identifiers

PMID37249312
PMCPMC10403961
OpenAlexW4378745129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.