Evidence map›Paper›PMID 37249046›Full record

ArticleVeterinary medicine and science2023

Evaluation of the short-term echocardiographic effects of two loop diuretics, furosemide and torsemide, in a group of dogs.

Farzaneh Hosseini, Zeinab Mahmoudi Filabadi, Peter B Hill, Morteza Hosseininejad

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Farzaneh HosseiniFaculty of Veterinary Medicine, Department of Clinical Sciences, Shahrekord University, Shahrekord, Iran.
Zeinab Mahmoudi FilabadiFaculty of Veterinary Medicine, Department of Clinical Sciences, Shahrekord University, Shahrekord, Iran.
Peter B HillSchool of Veterinary and Animal Sciences, The University of Adelaide, Adelaide, Australia.
Morteza HosseininejadFaculty of Veterinary Medicine, Department of Clinical Sciences, Shahrekord University, Shahrekord, Iran.ORCID 0000-0002-0568-518X
Shahrekord University · IRThe University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo loop diuretics, torsemide and frusemide, can affect the urinary system and consequently the cardiordiovascular haemodynamics in different ways.

objectivesThis study compared a number of echocardiographic parameters and systemic arterial blood pressure (ABP) changes following administration of furosemide or torsemide.

methodsFive shelter dogs underwent transthoracic two-dimensional M-mode echocardiography to obtain the following measurements: left ventricular internal dimension at end-systole (LVIDs), left ventricular internal dimension at end-diastole (LVIDd), fractional shortening (FS), heart rate (HR) and the distance between the mitral valve socket and the ventricle wall (septal to E Point, SEP). Arterial blood pressure was measured using the oscillometric method. Measurements recorded before treatment (baseline data) were compared to those after the dogs received furosemide (5 mg/kg) or torsemide (0.5 mg/kg).

resultsTorsemide significantly reduced blood pressure 1 h after administration, but this was not seen with furosemide. Fractional shortening, LVIDd and SEP decreased following both treatments, but there were no significant differences between the treatment groups. Torsemide increased heart rate above that seen in the furosemide groups.

conclusionsThe results of this study indicate that 1 h after administration, torsemide increases heart rate and decreases blood pressure when compared to furosemide, but both drugs have similar effects on measured cardiovascular indices.

Indexed as

FurosemideSodium Potassium Chloride Symporter InhibitorsAnimalsDiureticsDogsEchocardiographySulfonamidesTorsemideDiureticsFurosemideSodium Potassium Chloride Symporter InhibitorsSulfonamidesTorsemideblood pressurecaninediureticsechocardiographyfrusemidetorsemide

Identifiers

PMID37249046
PMCPMC10357252
OpenAlexW4378746268

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.