ArticlePsychiatry investigation2023
Prevalence and Correlates of Comorbid Posttraumatic Stress Disorder in Schizophrenia-Spectrum Disorder: A Systematic Review and Meta-Analysis.
Article in Psychiatry investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Risk Factors for Posttraumatic Stress Disorder in Mexican Psychiatric Trauma Survivors.Actas espanolas de psiquiatria · 2026Observational
- Exploring Group Differences in Attenuated Symptoms and Functioning Between Clinical High-Risk Individuals With and Without Posttraumatic Stress Disorder.Early intervention in psychiatry · 2026Article
- Targeting Sleep to Improve Outcomes in Psychosis: Digital and Non-Pharmacological Interventions.Medicina (Kaunas, Lithuania) · 2026Review
- Personality and Psychotic-Like Features in Post-Traumatic Stress Disorder With Severe Depression: An Minnesota Multiphasic Personality Inventory-2 Schizophrenia Scale Analysis.Psychiatry investigation · 2026Article
- Trauma descriptions and lived experiences: a phenomenological exploratory study among patients with severe mental illness in Botswana.BMC psychiatry · 2026Article
- Cultural adaptation of a brief psychological intervention for PTSD in severe mental illness: a Botswana context.Global mental health (Cambridge, England) · 2025Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSchizophrenia-spectrum disorders and posttraumatic stress disorder (PTSD) share common clinical manifestations, genetic vulnerability, and environmental risk factors. We aimed to conduct a systematic review and meta-analysis of the comorbid prevalence of PTSD among schizophrenia-spectrum disorders.
methodsWe performed a meta-analysis to identify possible contributing factors to the heterogeneity among these studies. We systematically searched electronic databases with no restrictions on language of articles.
resultsWe extracted 24 samples (18 for current prevalence and 6 for lifetime prevalence) from 22 studies and used a random effects model to estimate the pooled prevalence of PTSD among schizophrenia-spectrum disorders. The current and life prevalence of comorbid PTSD was 10.6% (95% confidence interval [CI]=6.3%-17.3%) and 13.0% (95% CI=5.3%-28.6%), respectively. Studies assessing psychotic experiences/involuntary admission reported the highest prevalence of comorbid PTSD (57.1%, 95% CI=43.6%-59.7%), whereas those assessing various anxiety disorders reported the lowest prevalence (1.1%, 95% CI=1.0%-5.5%). Heterogeneities of the subgroup analysis by similar objectives were largely homogeneous (I2=7.1-34.1). In the qualitative assessment, only two studies (9.1%) were evaluated as having a low risk of bias.
conclusionOur results showed that a careful approach with particular attention to assessing PTSD is essential to reliably estimate the prevalence of PTSD comorbid with schizophrenia-spectrum disorders. The reason for the wide discrepancy in the prevalence of comorbid PTSD among the four groups of studies should be addressed in future research.
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