Evidence map›Paper›PMID 37248583›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2023

[Decreased Expression of Mitochondrial Calcium Uptake Protein 1 Leads to Skeletal Muscle Dysfunction in Septic Mice].

Xue-Xin Li, Song-Lin Wu, Fa-Sheng Guan, Li Liu

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Calcium signaling in mitochondrial intermembrane space.Biochemical Society transactions · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xue-Xin LiDepartment of Anesthesia, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Song-Lin WuDepartment of Anesthesia, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Fa-Sheng GuanDepartment of Anesthesia, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Li LiuDepartment of Anesthesia, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To observe the effect of sepsis on skeletal muscle function and to explore the role of skeletal muscle mitochondrial calcium uptake protein 1 (MICU1). Methods: A total of 40 specific-pathogen-free (SPF) healthy male C57BL/6J mice were randomly assigned to 4 groups, a sham operation group (Sham group, Results: Compared with mice in the Sham group, mice in the CLP group showed decreased body weight ( Conclusion: Sepsis leads to skeletal muscle dysfunction, which is related to the decrease in mitochondrial MICU1 expression.

Indexed as

SepsisTumor Necrosis Factor-alphaAnimalsCalciumCalcium-Binding ProteinsInterleukin-6MaleMiceMice, Inbred C57BLMitochondrial Membrane Transport ProteinsMuscle, SkeletalMuscular AtrophyCalciumCalcium-Binding ProteinsInterleukin-6MICU1 protein, mouseMitochondrial Membrane Transport ProteinsTumor Necrosis Factor-alphaMitochondriaMitochondrial calcium uptake protein 1Muscle weaknessSepsisSkeletal muscles

Identifiers

PMID37248583
PMCPMC10475437
OpenAlexW4378746270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.