Evidence map›Paper›PMID 37248444›Full record

ArticleBMC neurology2023

Lymphomatoid granulomatosis with the central nervous system involvement as the main manifestation: a case report.

Dawei Chen, Jing Zhou, Weiwen Lu, Liuzhe Lu, Bo Chen, Wenzhong Li

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dawei ChenDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin Province, China. cdw@jlu.edu.cn.
Jing ZhouDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin Province, China.
Weiwen LuDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin Province, China.
Liuzhe LuDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin Province, China.
Bo ChenDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin Province, China.
Wenzhong LiDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin Province, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLymphomatoid granulomatosis (LyG) is a rare extralymphatic lymphoproliferative disease characterized by lymphocytic invasion into vascular walls and damage to blood vessels. The lungs are affected in 90% of LyG cases, followed by the skin, central nervous system (CNS), kidneys and liver. CASE PRESENTATION: Here we report a case of a young woman with LyG, with CNS involvement as the initial clinical manifestation. Computer tomography (CT) scans showed multiple nodular, patchy and flocculent high-density shadows in both lungs without mediastinal lymph node enlargement. Magnetic resonance imaging (MRI) scans showed multiple abnormal signal intensities in the right cerebellar hemisphere, frontal, parietal and temporal lobes, and dorsal brainstem, which became patchy and annular after enhancement. The post-operative pathological analysis of lesion samples confirmed the diagnosis of grade II LyG.

conclusionsLyG should be concerned in young adults showing multiple radiological brain and lung lesions. Resection and postoperative medication of steroid hormones and IFN-α may be effective in the treatment of LyG.

Indexed as

Brain NeoplasmsLymphomatoid GranulomatosisBrainCentral Nervous SystemFemaleHumansLungYoung AdultCentral nervous systemIFN-αImmunohistochemistryLymphomatoid granulomatosis

Identifiers

PMID37248444
PMCPMC10226225
OpenAlexW4378715045

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.