ArticleNature immunology2023
Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.
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Article in Nature immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Atypical B cells and inflammatory profiles delineate immunity to influenza vaccination in First Nations and non-Indigenous people with chronic multimorbidity.Nature communications · 2026Article
- Long-term kinetics of anti-RBD IgG antibodies 16 months after COVID-19 vaccination in Morocco: a longitudinal cohort study.Scientific reports · 2026Article
- Building better antibody responses: The interplay of infection, vaccination, and immune imprinting.PNAS nexus · 2026Review
- Dysregulated inflammation in solid tumor malignancy patients shapes polyfunctional antibody responses to COVID-19 vaccination.NPJ vaccines · 2025Article
- HLA-B*15:01-positive severe COVID-19 patients lack CD8Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Humoral Response to the Third Dose of SARS-CoV-2 Vaccine Among Dialysis Patients: A Breakthrough Infection Case-Control Study.Vaccines · 2025Article
- Article
- SARS-CoV-2 antibody immunity across three continents: the West Africa, West Indies, West London Consortium.medRxiv : the preprint server for health sciences · 2025Article
- Deconvoluting TCR-dependent and -independent activation is vital for reliable Ag-specific CD4Science advances · 2025Article
- Effect of Bacille Calmette-Guérin vaccination on immune responses to SARS-CoV-2 and COVID-19 vaccination.Clinical & translational immunology · 2025Article
- Recognising the heterogeneity of Indigenous Peoples during the COVID-19 pandemic: a scoping review across Canada, Australia, New Zealand and the USA.BMJ public health · 2024Article
- Article
- Defining the balance between optimal immunity and immunopathology in influenza virus infection.Nature reviews. Immunology · 2024Review
- Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population.Science advances · 2024Article
- SARS-CoV-2-specific CD8Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Levels and functionality of Pacific Islanders' hybrid humoral immune response to BNT162b2 vaccination and delta/omicron infection: A cohort study in New Caledonia.PLoS medicine · 2024Article
- Quantifying Disparities in COVID-19 Vaccination Rates by Rural and Urban Areas: Cross-Sectional Observational Study.JMIR public health and surveillance · 2024Observational
- Scientific highlights of the 9th ESWI Influenza Conference.One health outlook · 2024Article
- Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19.Frontiers in immunology · 2024Article
- Immune response and severity of Omicron BA.5 reinfection among individuals previously infected with different SARS-CoV-2 variants.Frontiers in cellular and infection microbiology · 2023Article
Corrections and comments
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Authors and funding
46 authors at 16 institutions in 3 countries.
Wuji ZhangDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0001-7460-4956
Lukasz KedzierskiDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-0203-1057
Brendon Y ChuaDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
Mark MayoMenzies School of Health Research, Darwin, Northern Territory, Australia.
Claire LonziMenzies School of Health Research, Darwin, Northern Territory, Australia.
Vanessa RigasMenzies School of Health Research, Darwin, Northern Territory, Australia.
Bianca F MiddletonMenzies School of Health Research, Darwin, Northern Territory, Australia.
Hayley A McQuiltenDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-7089-5300
Louise C RowntreeDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
Lilith F AllenDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
Ruth A PurcellDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0001-6378-5114
Hyon-Xhi TanDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-1064-3934
Jan PetersenInfection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Priyanka ChaurasiaInfection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0002-3755-159X
Francesca MordantDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-3754-2642
Mikhail V PogorelyyDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Anastasia A MinervinaDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jeremy Chase CrawfordDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-4096-6048
Griffith B PerkinsCentral and Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0001-8559-5872
Eva ZhangDepartment of Gastroenterology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Stephanie GrasInfection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0001-7416-038X
E Bridie ClemensDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
Jennifer A JunoDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-9072-1017
Jennifer AudsleyDepartment of Infectious Diseases, Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Victoria, Australia.
David S KhouryKirby Institute, University of New South Wales, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-2663-1551
Natasha E HolmesDepartment of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia.
Irani ThevarajanDepartment of Infectious Diseases, Peter Doherty Institute for Infection and Immunity, University of Melbourne and Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Kanta SubbaraoDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
Florian KrammerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-4121-776X
Allen C ChengDepartment of Infectious Diseases, Alfred Hospital and Central Clinical School and School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Miles P DavenportKirby Institute, University of New South Wales, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-4751-1831
Branka Grubor-BaukAdelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia.
P Toby CoatesCentral and Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Britt ChristensenAdelaide Medical School, University of Adelaide, Adelaide, South Australia, Australia.
Paul G ThomasDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0001-7955-0256
Adam K WheatleyDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-5593-9387
Stephen J KentDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-8539-4891
Jamie RossjohnInfection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0002-2020-7522
Amy W ChungDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-0020-9704
John BoffaCentral Australian Aboriginal Congress, Alice Springs, Northern Territory, Australia.
Adrian MillerIndigenous Engagement, CQUniversity, Townsville, Queensland, Australia.
Sarah LynarMenzies School of Health Research, Darwin, Northern Territory, Australia.
Jane NelsonMenzies School of Health Research, Darwin, Northern Territory, Australia.
Thi H O Nguyen *Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia. tho.nguyen@unimelb.edu.au.ORCID http://orcid.org/0000-0002-9294-7693
Jane Davies *Menzies School of Health Research, Darwin, Northern Territory, Australia. jane.davies@menzies.edu.au.ORCID http://orcid.org/0000-0002-3843-837X
Katherine Kedzierska *Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia. kkedz@unimelb.edu.au.ORCID http://orcid.org/0000-0001-6141-335X
The University of Melbourne · AUMenzies School of Health Research · AUSt. Jude Children's Research Hospital · USAustralian Regenerative Medicine Institute · AUThe Royal Melbourne Hospital · AURoyal Adelaide Hospital · AUUNSW Sydney · AUAustin Health · AUAustralian Research Council · AUCentral Land Council · AUCentral Queensland University · AUIcahn School of Medicine at Mount Sinai · USLa Trobe University · AUMonash Health · AUThe University of Adelaide · AUVictorian Infectious Diseases Reference Laboratory · AU
Funding
DECODING THE INTERACTIONS BETWEEN T CELL RECEPTORS AND PEPTIDE-MHCR01AI136514 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Paul G. Thomas · 2018 to 2026
$6.9MDYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSESU01AI150747 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI, ANTIA, RUSTOM NOSHIR · 2020 to 2024
$5.9MNIAID NIH HHS R01 AI136514NIAID NIH HHS U01 AI150747
Abstract
High-risk groups, including Indigenous people, are at risk of severe COVID-19. Here we found that Australian First Nations peoples elicit effective immune responses to COVID-19 BNT162b2 vaccination, including neutralizing antibodies, receptor-binding domain (RBD) antibodies, SARS-CoV-2 spike-specific B cells, and CD4
Indexed as
COVID-19COVID-19 VaccinesAntibodies, NeutralizingAntibodies, ViralAustraliaBNT162 VaccineCD8-Positive T-LymphocytesHumansImmunityImmunoglobulin GSARS-CoV-2VaccinationAntibodies, NeutralizingAntibodies, ViralBNT162 VaccineCOVID-19 VaccinesImmunoglobulin G
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