Evidence map›Paper›PMID 37248397›Full record

ReviewNature cancer2023

Understanding inequities in precision oncology diagnostics.

Ritika Dutta, Mounica Vallurupalli, Quinn McVeigh, Franklin W Huang, Timothy R Rebbeck

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. Emerging trends in the global burden of colorectal cancer.Nature reviews. Clinical oncology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ritika Dutta *Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Mounica Vallurupalli *Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Quinn McVeighDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Franklin W HuangCancer Program, Broad Institute, Cambridge, MA, USA. franklin.huang@ucsf.edu.ORCID http://orcid.org/0000-0001-5447-0436
Timothy R RebbeckDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. timothy_rebbeck@dfci.harvard.edu.ORCID http://orcid.org/0000-0002-4799-1900
Broad Institute · USBrigham and Women's Hospital · USHarvard University · US

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI JENNIFER W MACK · 1985 to 2026
$330.6M
NCI NIH HHS P30 CA006516
6 · The paper itself

Abstract

Advances in molecular diagnostics have enabled the identification of targetable driver pathogenic variants, forming the basis of precision oncology care. However, the adoption of new technologies, such as next-generation sequencing (NGS) panels, can exacerbate healthcare disparities. Here, we summarize data on use patterns of advanced biomarker testing, highlight the disparities in both accessing NGS testing and using this data to match patients to appropriate personalized therapies and propose multidisciplinary strategies to address inequities looking forward.

Indexed as

NeoplasmsHigh-Throughput Nucleotide SequencingHumansMedical OncologyPrecision Medicine

Identifiers

PMID37248397
OpenAlexW4378648912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.