Evidence map›Paper›PMID 37248277›Full record

ArticleScientific reports2023

Anti-Toxoplasma gondii activity of Trametes versicolor (Turkey tail) mushroom extract.

Homa Nath Sharma, Jonathan Catrett, Ogechi Destiny Nwokeocha, Melissa Boersma, Michael E Miller, Audrey Napier, Boakai K Robertson, Daniel A Abugri

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Apigeninidin chloride disruptsFrontiers in cellular and infection microbiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Homa Nath Sharma *Department of Biological Sciences, College of Science, Technology, Engineering and Mathematics, Alabama State University, Montgomery, AL, 36104, USA.
Jonathan Catrett *Enterprise State Community College, Enterprise, AL, USA.
Ogechi Destiny NwokeochaDepartment of Chemistry, College of Arts and Sciences, Tuskegee University, Tuskegee, AL, 36088, USA.
Melissa BoersmaDepartment of Chemistry and Biochemistry, College of Science and Mathematics (COSAM), Auburn University, Auburn, AL, 36849, USA.
Michael E MillerAuburn University Research Instrumentation Facility, Harrison College of Pharmacy, Auburn University, Auburn, AL, 36849, USA.
Audrey NapierDepartment of Biological Sciences, College of Science, Technology, Engineering and Mathematics, Alabama State University, Montgomery, AL, 36104, USA.
Boakai K RobertsonDepartment of Biological Sciences, College of Science, Technology, Engineering and Mathematics, Alabama State University, Montgomery, AL, 36104, USA.
Daniel A AbugriDepartment of Biological Sciences, College of Science, Technology, Engineering and Mathematics, Alabama State University, Montgomery, AL, 36104, USA. dabugri@alasu.edu.
Alabama State University · USAuburn University · USEnterprise State Community College · USTuskegee University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasma gondii (T. gondii) infection continues to rise globally in humans and animals with high socioeconomic and public health challenges. Current medications used against T. gondii infection are limited in efficacy, safety, and affordability. This research was conducted to assess the higher fungi extract effect on T. gondii tachyzoites growth in vitro and possibly decipher its mechanism of action. Furthermore, we evaluated the extract's effect on human foreskin fibroblast viability. The methanol extracts of Turkey tail (TT) mushroom was tested against T. gondii tachyzoites growth using an RH-RFP type I strain that expresses red fluorescent protein throughout culture in a dose-dependent manner using a fluorescent plate reader. Similarly, we tested the effect of the extract on host cell viability. We observed that TT extract inhibited tachyzoites growth with a 50% minimum inhibitory concentration (IC

Indexed as

AgaricalesToxoplasmaToxoplasmosisAnimalsHumansMethanolPolyporaceaeTrametesMethanol

Identifiers

PMID37248277
PMCPMC10225767
OpenAlexW4378651719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.