Evidence map›Paper›PMID 37247959›Full record

ArticleBMJ open2023

Feasibility and acceptability pilot of video-based direct observed treatment (vDOT) for supporting antitubercular treatment in South India: a cohort study.

Rashmi Rodrigues, Suman Sarah Varghese, Mohammed Mahrous, Anil Ananthaneni Kumar, Mohammed Naseer Ahmed, George D'Souza

Abstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rashmi RodriguesCommunity Health, St John's National Academy of Health Sciences, Bangalore, Karnataka, India rashmijr@gmail.com.
Suman Sarah VargheseSt. John's Research Institute, St John's National Academy of Health Sciences, Bangalore, Karnataka, India.ORCID 0000-0003-4437-4517
Mohammed MahrousIndependent Researcher, Bangalore, Karnataka, India.
Anil Ananthaneni KumarSt. John's Research Institute, St John's National Academy of Health Sciences, Bangalore, Karnataka, India.ORCID 0000-0003-0565-8752
Mohammed Naseer AhmedSt. John's Research Institute, St John's National Academy of Health Sciences, Bangalore, Karnataka, India.
George D'SouzaPulmonary Medicine, St John's National Academy of Health Sciences, Bangalore, Karnataka, India.

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectivesThe objective of this study was to assess the feasibility and acceptability of video-based anti-tuberculosis (TB) treatment adherence support in patients with TB (PwTB) in South India.

designAn exploratory cohort.

settingParticipants were recruited at the TB treatment centre (direct observed treatment short centre) of a tertiary-level teaching facility in Bangalore, Karnataka, South India.

participantsThe study enrolled 25 PwTB, with replacement. Adult PwTB who were on drug-sensitive treatment regimens were included, while those who had drug resistant TB were excluded from the study.

interventionParticipants received scheduled adherence reminders and were trained to videorecord themselves swallowing their medication via a mobile application. The application was automated to submit these videos for evaluation. Participants were followed up monthly till treatment completion or withdrawal. OUTCOME MEASURES: Adherence rate and acceptability of video-based directly observed treatment (vDOT).

resultsThe mean±SD age of the participants was 33±14 years, majority were females (16, 64%), residing in urban areas (24,96%), married (17, 68%) and had access to smart phones (23,92%). A total of 3193 person days of follow-up was completed; of the videos submitted within the first 6 months of enrollment (2501), 94% (2354/2501) were considered 'acceptable' and 16 (64%) participants were optimally adherent (ie, ≥80%). Participant videos improved in quality and a higher proportion met acceptability criteria over time. Twenty-one (84%) participants stated that they found the application easy to learn; 13 (52%) preferred vDOT over DOT. Mixed model logistic regression showed that those who are married are more likely have daily adherence to anti-TB treatment.

conclusionVideo-based mobile phone interventions are acceptable to PwTB and the ease of using the application increases with time. To provide patient-centred care, vDOT is a promising option that can be offered to patients for treatment support and adherence monitoring.

Indexed as

Medication AdherenceTuberculosisAdultAntitubercular AgentsCohort StudiesDirectly Observed TherapyFeasibility StudiesFemaleHumansIndiaMaleMiddle AgedYoung AdultAntitubercular AgentsEpidemiologyINTERNAL MEDICINEPublic health

Identifiers

PMID37247959
PMCPMC10230861

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.