Evidence map›Paper›PMID 37247566›Full record

ReviewCurrent opinion in microbiology2023

The emerging complexity of Chlamydia trachomatis interactions with host cells as revealed by molecular genetic approaches.

Robert J Bastidas, Raphael H Valdivia

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The multifunctionProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Review
  7. Autophagy: the misty lands ofFrontiers in cellular and infection microbiology · 2024
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robert J BastidasDepartment of Integrative Immunobiology, Duke University Medical Center, Durham, NC 27710, USA.
Raphael H ValdiviaDepartment of Integrative Immunobiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: raphael.valdivia@duke.edu.
Duke University · US

Funding

Functional characterization of early Chlamydia effectorsR01AI134891 · NIAID · DUKE UNIVERSITY · PI VALDIVIA, RAPHAEL H · 2018 to 2022
$2.4M
NIAID NIH HHS R01 AI134891
6 · The paper itself

Abstract

Chlamydia trachomatis (Ct) is an intracellular bacterial pathogen that relies on the activity of secreted proteins known as effectors to promote replication and avoidance of immune clearance. Understanding the contribution of Ct effectors to pathogenesis has proven to be challenging, given that these proteins often perform multiple functions during intracellular infection. Recent advances in molecular genetic analysis of Ct have provided valuable insights into the multifaceted nature of secreted effector proteins and their impact on the interaction between Ct and host cells and tissues. This review highlights significant findings from genetic analysis of Ct effector functions, shedding light on their diverse roles. We also discuss the challenges faced in this field of study and explore potential opportunities for further research.

Indexed as

Bacterial ProteinsChlamydia trachomatisHost-Pathogen InteractionsMolecular BiologyBacterial Proteins

Identifiers

PMID37247566
PMCPMC10988583
OpenAlexW4378554649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.