SynthesisAge and ageing2023
Does frailty status predict outcome in major trauma in older people? A systematic review and meta-analysis.
Synthesis in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Multidimensional Preinjury Health and 6-month Outcome After Traumatic Brain Injury in Older Adults Presenting With Mainly GCS 13-15.The Journal of head trauma rehabilitation · 2026Article
- Epidemiology of major work-related injuries in Abu Dhabi, United Arab Emirates: a 10-year retrospective study.BMJ open · 2026Article
- Antiresorptive Use and Risk of Hip Fracture in Older Women with Osteoporosis: Findings from a Real-World National Database of 21,332 Women.Journal of clinical medicine · 2026Article
- Predictive Performance of Trauma Scoring Systems for Mortality in Patients with High-Energy Trauma in the Emergency Department.Journal of clinical medicine · 2026Article
- Women With Low Falls Are Less Likely To Be Admitted to a Specialist Trauma Unit: A Single Centre Observational Study of Older Adults.ANZ journal of surgery · 2026Observational
- Frailty Screening in the Emergency Department Enables Personalized Multidisciplinary Care for Geriatric Trauma Patients.Journal of personalized medicine · 2026Review
- Frailty as a predictor of discharge destination and long-term function in older adults with burn injury.International journal of burns and trauma · 2026Article
- Skeletal Muscle Quality Evaluation for Prognostic Stratification in the Emergency Department of Patients ≥65 Years with Major Trauma.Journal of clinical medicine · 2025Article
- Major trauma in the elderly: unique challenges and considerations.BJA education · 2025Review
- Association of frailty with clinical and financial outcomes of hospitalization for non-operative trauma.Surgery open science · 2025Article
- Does frailty scoring help to predict outcomes in older patients with major trauma? A retrospective study at a major trauma centre.Emergency medicine Australasia : EMA · 2025Observational
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- Age Impacts Clinical and Patient-Reported Outcomes following Postmastectomy Breast Reconstruction.Plastic and reconstructive surgery · 2025Article
- Is the Timing of Surgery Associated With the Risk of Mortality Among Older Adults Undergoing Operative Hip Fracture Repair?Geriatric orthopaedic surgery & rehabilitation · 2025Article
- Efficacy of the Geriatric Trauma Outcome Score (GTOS) in Predicting Mortality in Trauma Patients: A Retrospective Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2024Article
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- Decreased Glycocalyx Shedding on Presentation in Hemorrhaging Geriatric Trauma Patients.The Journal of surgical research · 2024Article
- Prolonged Hospital Stay in Elderly Blunt Colorectal Trauma: A National Trauma Data Bank Analysis.Journal of emergencies, trauma, and shockArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe incidence of major trauma in older people is increasing. Frailty is likely to be a factor that influences the outcomes of trauma. We conducted a systematic review aiming to investigate whether frailty affects major trauma outcomes in older people and whether it is more predictive than age.
methodsObservational studies investigating frailty, major trauma severity and outcomes were eligible. We searched electronic databases (Ovid MEDLINE, PubMed, Ovid EMBASE and CINAHL) from 2010 to 01 January 2023. We used Joanna Briggs Institute software to assess the risk of bias and conduct meta-analyses of the relationships between frailty status and outcomes. We used a narrative synthesis to compare the predictive value of frailty and age.
resultsTwelve studies were eligible for meta-analyses. In-hospital mortality (odds ratio (OR) = 1.12, 95% confidence interval (CI) 1.05, 1.19), length of stay (OR = 2.04, 95% CI 1.51, 2.56), discharge to home (OR = 0.58, 95% CI 0.53, 0.63) and in-hospital complications (OR = 1.17, 95% CI 1.10, 1.24) were all associated with frailty. Frailty was found to be a more consistent predictor of adverse outcomes and mortality in older trauma patients than injury severity and age in six studies that reported multivariate regression analysis. DISCUSSION: Older trauma patients with frailty have higher in-hospital mortality rates, prolonged hospital stays, in-hospital complications and adverse discharge disposition. Frailty is a better predictor of adverse outcomes than age in these patients. Frailty status is likely to be a useful prognostic variable in guiding patient management and stratifying clinical benchmarks and research trials.
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