Evidence map›Paper›PMID 37247403›Full record

ArticleAge and ageing2023

Attainment of NICE blood pressure targets among older people with newly diagnosed hypertension: nationwide linked electronic health records cohort study.

Oliver Todd, Oliver Johnson, Chris Wilkinson, Joe Hollinghurst, Tatendashe B Dondo, Mohammad E Yadegarfar, James P Sheppard, Richard J McManus, Chris P Gale, Andrew Clegg

Abstract read
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Article in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Oliver ToddAcademic Unit for Ageing and Stroke Research, University of Leeds, Leeds, England LS2 9LH, UK.
Oliver JohnsonSchool of Medicine, University of Leeds, Leeds, England, LS2 9LH, UK.
Chris WilkinsonHull York Medical School, University of York, York, England YO10 5DD, UK.
Joe HollinghurstHealth Data Research UK (HDR-UK), University of Swansea, Swansea, Wales SA2 8PP, UK.
Tatendashe B DondoLeeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, England LS2 9LH, UK.
Mohammad E YadegarfarSchool of Life Course & Population Sciences, King's College London, London, England WC2R 2LS, UK.
James P SheppardNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, England OX2 6GG, UK.
Richard J McManusNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, England OX2 6GG, UK.
Chris P GaleLeeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, England LS2 9LH, UK.
Andrew CleggAcademic Unit for Ageing and Stroke Research, University of Leeds, Leeds, England LS2 9LH, UK.

Funding

Department of HealthWellcome Trust 211182/Z/18/Z
6 · The paper itself

Abstract

backgroundit is not known if clinical practice reflects guideline recommendations for the management of hypertension in older people and whether guideline adherence varies according to overall health status.

aimsto describe the proportion of older people attaining National Institute for Health and Care Excellence (NICE) guideline blood pressure targets within 1 year of hypertension diagnosis and determine predictors of target attainment.

methodsa nationwide cohort study of Welsh primary care data from the Secure Anonymised Information Linkage databank including patients aged ≥65 years newly diagnosed with hypertension between 1st June 2011 and 1st June 2016. The primary outcome was attainment of NICE guideline blood pressure targets as measured by the latest blood pressure recording up to 1 year after diagnosis. Predictors of target attainment were investigated using logistic regression.

resultsthere were 26,392 patients (55% women, median age 71 [IQR 68-77] years) included, of which 13,939 (52.8%) attained a target blood pressure within a median follow-up of 9 months. Success in attaining target blood pressure was associated with a history of atrial fibrillation (OR 1.26, 95% CI 1.11, 1.43), heart failure (OR 1.25, 95% CI 1.06, 1.49) and myocardial infarction (OR 1.20, 95% CI 1.10, 1.32), all compared to no history of each, respectively. Care home residence, the severity of frailty, and increasing co-morbidity were not associated with target attainment following adjustment for confounder variables.

conclusionsblood pressure remains insufficiently controlled 1 year after diagnosis in nearly half of older people with newly diagnosed hypertension, but target attainment appears unrelated to baseline frailty, multi-morbidity or care home residence.

Indexed as

FrailtyHypertensionAgedAntihypertensive AgentsBlood PressureCohort StudiesElectronic Health RecordsFemaleHumansMaleAntihypertensive Agentsblood pressurefrailtyhypertensionolder peopletreatment target

Identifiers

PMID37247403
PMCPMC10226747

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.