Evidence map›Paper›PMID 37247385›Full record

ArticleMolecular pain

Spinal microRNA-134-5p targets glutamate receptor ionotropic kainate 3 to modulate opioid induced hyperalgesia in mice.

Zhen Wang, Yao Yao, Yuzhu Tao, Peixin Fan, Yonghao Yu, Keliang Xie, Guolin Wang

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Epigenetic mechanisms of HIV and opioid-induced neuropathology: Potential therapies and interventions.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Zhen WangDepartment of Anesthesiology, Tianjin Research Institute of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Yao YaoDepartment of Anesthesiology, Tianjin Research Institute of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Yuzhu TaoDepartment of Anesthesiology, Tianjin Huanhu Hospital, Tianjin, China.
Peixin FanDepartment of Animal and Dairy Science, Mississippi State University, Starkville, MS, USA.
Yonghao YuDepartment of Anesthesiology, Tianjin Research Institute of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Keliang XieDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Guolin WangDepartment of Anesthesiology, Tianjin Research Institute of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.ORCID 0000-0001-7867-2091
Tianjin Medical University General Hospital · CNBiocom · USTianjin Huanhu Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Analgesics, OpioidMicroRNAsAnimalsEpigenesis, GeneticHyperalgesiaIn Situ Hybridization, FluorescenceKainic AcidMicePainPiperidinesReceptors, GlutamateRemifentanilSufentanilAnalgesics, OpioidKainic AcidMicroRNAsMirn134 microRNA, mousePiperidinesReceptors, GlutamateRemifentanilSufentanildendritic spine plasticityGRIK3kainate receptorsmiR-134-5premifentanil-induced hyperalgesiasufentanil

Identifiers

PMID37247385
PMCPMC10240872
OpenAlexW4378713863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.