Evidence map›Paper›PMID 37247135›Full record

ArticleMetabolic brain disease2023

Membrane-stabilizing and protective effects of curcumin in a rotenone-induced rat model of Parkinson disease.

L V Darbinyan, K V Simonyan, L E Hambardzumyan, M A Simonyan, R M Simonyan, L P Manukyan

Abstract read
PubMed Publisher
In one paragraph

Article in Metabolic brain disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Lead Phytomolecules for Treating Parkinson's Disease.Central nervous system agents in medicinal chemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

L V DarbinyanSensorimotor Integration Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.ORCID 0000-0002-5364-2838
K V SimonyanNeuroendocrine Relationships Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia. karensimonyan1986@yahoo.com.ORCID 0000-0001-6884-6545
L E HambardzumyanSensorimotor Integration Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.ORCID 0000-0002-3694-4068
M A SimonyanH. Buniatyan Institute of Biochemistry NAS RA, 0014, Yerevan, Armenia.ORCID 0009-0001-5762-4573
R M SimonyanH. Buniatyan Institute of Biochemistry NAS RA, 0014, Yerevan, Armenia.ORCID 0000-0002-2326-3626
L P ManukyanSensorimotor Integration Lab, Orbeli Institute of Physiology NAS RA, 0028, Yerevan, Armenia.ORCID 0009-0007-7605-5189
L. A. Orbeli Institute of Physiology NAS RA · AMH.Buniatian Institute of Biochemistry · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson disease (PD) is a chronic progressive neurodegenerative disease characterized by both motor and non-motor features. Numerous risk factors (oxidative stress, free radical formation, and several environmental toxins) have been associated with PD. The experimental studies were carried out under in vivo conditions. Biochemical data analysis indicated that compared with the parameters of control (C) rats, rotenone-induced PD rats showed a significant decrease in the specific content of the total fraction of isoforms of O

Indexed as

CurcuminNeurodegenerative DiseasesNeuroprotective AgentsParkinson DiseaseAnimalsDisease Models, AnimalOxidative StressRatsRotenoneCurcuminNeuroprotective AgentsRotenoneCurcuminNADPH-containing lipoproteinParkinson disease

Identifiers

PMID37247135
OpenAlexW4378620041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.