Evidence map›Paper›PMID 37247044›Full record

ArticleAIDS and behavior2023

A Retrospective Comparison of HIV Pre-exposure Prophylaxis (PrEP) Outcomes Between a Pharmacist-led Telehealth Clinic and In-person Clinic in a Veteran Population.

Kellen Greenwell, Randolph Fugit, Lindsay Nicholson, Jason Wright

Abstract readComparative Study
In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kellen GreenwellDepartment of Pharmacy, VA Eastern Colorado Health Care System, 1700 N Wheeling St, Aurora, CO, 80045, USA.ORCID http://orcid.org/0000-0001-7180-8400
Randolph FugitDepartment of Pharmacy, VA Eastern Colorado Health Care System, 1700 N Wheeling St, Aurora, CO, 80045, USA.ORCID http://orcid.org/0000-0001-8680-9246
Lindsay NicholsonDepartment of Medicine, Division of Infectious Diseases, VA Eastern Colorado Health Care System, 1700 N Wheeling St, Aurora, CO, 80045, USA.ORCID http://orcid.org/0000-0001-5581-2792
Jason WrightDepartment of Pharmacy, VA Eastern Colorado Health Care System, 1700 N Wheeling St, Aurora, CO, 80045, USA. Jason.Wright5@va.gov.ORCID http://orcid.org/0000-0002-1145-4900

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pre-exposure prophylaxis (PrEP) reduces human immunodeficiency virus (HIV) transmission through sexual contact by at least 90% when taken as prescribed. This retrospective cohort study evaluated differences in adherence to PrEP medication and monitoring between the physician- and nurse practitioner (NP)-led in-person setting and the pharmacist-led telehealth setting among patients followed by the infectious diseases clinic at the VA Eastern Colorado Health Care System from July 2012 to February 2021. The primary outcomes were PrEP tablets filled per person-year, serum creatinine (SCr) tests per person-year, and HIV screens per person-year. Secondary outcomes included sexually transmitted infection (STI) screens per person-year and patients lost to follow-up.149 patients were included in the study, with 167 person-years in the in-person cohort and 153 person-years in the telehealth cohort. Adherence to PrEP medications and monitoring was similar between in-person and telehealth clinics. PrEP tablets filled per person-year was 324 in the in-person cohort and 321 in the telehealth cohort (RR = 0.99; 95% CI, 0.98-1.00). SCr screens per person-year was 3.51 in the in-person cohort and 3.37 in the telehealth cohort (RR = 0.96; 95% CI, 0.85-1.07). HIV screens per person-year was 3.55 in the in-person cohort and 3.38 in the telehealth cohort (RR = 0.95; 95% CI, 0.85-1.07). There were no new HIV infections. Additionally, patients were less likely to be lost to follow-up when followed via telehealth (11.9% vs. 30.0%), Χ2 (1, N = 149) = 6.85, p = 0.009. These findings indicate that pharmacist-driven delivery of PrEP via telehealth can be used to increase access to PrEP without sacrificing quality of care.

Indexed as

Anti-HIV AgentsHIV InfectionsPharmacistsPre-Exposure ProphylaxisTelemedicineVeteransAdultAmbulatory Care FacilitiesColoradoFemaleHumansMaleMedication AdherenceMiddle AgedRetrospective StudiesAnti-HIV AgentsAdherenceDescovyHIVMedication possession ratioPre-exposure prophylaxis (PrEP)TelehealthTruvada

Identifiers

PMID37247044
PMCPMC10226437

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.