Evidence map›Paper›PMID 37246485›Full record

ArticleMagnetic resonance in medicine2023

Direct synthesis of multi-contrast brain MR images from MR multitasking spatial factors using deep learning.

Shihan Qiu, Sen Ma, Lixia Wang, Yuhua Chen, Zhaoyang Fan, Franklin G Moser, Marcel Maya, Pascal Sati, Nancy L Sicotte, Anthony G Christodoulou and 2 more

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. ACCELERATING QUANTITATIVE MRI USING SUBSPACE MULTISCALE ENERGY MODEL (SS-MUSE).Proceedings. IEEE International Symposium on Biomedical Imaging · 2025
    Article
  5. Cramér-Rao Bound Optimized Subspace Reconstruction in Quantitative MRI.IEEE transactions on bio-medical engineering · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Shihan QiuBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0003-4993-2987
Sen MaBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0001-9715-7706
Lixia WangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Yuhua ChenBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Zhaoyang FanBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0002-2693-0260
Franklin G MoserDepartment of Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Marcel MayaDepartment of Imaging, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Pascal SatiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Nancy L SicotteDepartment of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Anthony G ChristodoulouBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0002-9334-8684
Yibin XieBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Debiao LiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Cedars-Sinai Medical Center · USUniversity of Southern California · US

Funding

Motion-Resolved, Comprehensive Quantitative Tissue Characterization Using MR MultitaskingR01EB028146 · NIBIB · CEDARS-SINAI MEDICAL CENTER · PI CHRISTODOULOU, ANTHONY G, LI, DEBIAO · 2019 to 2022
$2.5M
NIBIB NIH HHS R01 EB028146
6 · The paper itself

Abstract

purposeTo develop a deep learning method to synthesize conventional contrast-weighted images in the brain from MR multitasking spatial factors.

methodsEighteen subjects were imaged using a whole-brain quantitative T

resultsThe deep-learning synthetic images showed comparable contrasts of brain tissues with the reference images from true acquisitions and were substantially better than the Bloch-equation-based synthesis results. Averaging on the three contrasts, the deep learning synthesis achieved normalized root mean square error = 0.184 ± 0.075, peak SNR = 28.14 ± 2.51, and structural-similarity index = 0.918 ± 0.034, which were significantly better than Bloch-equation-based synthesis (p < 0.05). Radiologists' rating results show that compared with true acquisitions, deep learning synthesis had no notable quality degradation and was better than Bloch-equation-based synthesis.

conclusionA deep learning technique was developed to synthesize conventional weighted images from MR multitasking spatial factors in the brain, enabling the simultaneous acquisition of multiparametric quantitative maps and clinical contrast-weighted images in a single scan.

Indexed as

Deep LearningBrainHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingNeural Networks, Computerbraindeep learningimage synthesisMR imagingquantitative imaging

Identifiers

PMID37246485
PMCPMC10524469
OpenAlexW4378640028

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.