Evidence map›Paper›PMID 37246232›Full record

ArticleBMC oral health2023

Salivary stimulatory effect of novel low level transcutaneous electro neurostimulator in geriatric patients with xerostomia.

Ramya Ramadoss, Rajkumar Krishnan, Swarnalakshmi Raman, Rajashree Padmanaban, Nagarathinam Anbuelangovan, Rajalakshmanan Eswaramoorthy

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Ramya RamadossDepartment of Oral Biology, Saveetha Dental College, Chennai, India. ramyar.sdc@saveetha.com.
Rajkumar KrishnanDepartment of Oral Pathology, SRM Dental College, Chennai, India.
Swarnalakshmi RamanDepartment of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Rajashree PadmanabanCentre of Advanced Study in Crystallography & Biophysics, University of Madras, Chennai, India.
Nagarathinam AnbuelangovanDepartment of Oral Pathology, SRM Dental College, Chennai, India.
Rajalakshmanan EswaramoorthyDepartment of Biomaterials, Centre of Molecular Medicine and Diagnostics (COMMAND), Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India. rajalakshmanan.e@gmail.com.
Saveetha University · INSRM Dental College · INTokushima University · JPUniversity of Madras · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundXerostomia (dryness of the mouth) is one of the most common long-term consequences of ageing, and it causes a tremendous impact on the function and morphology of the salivary ductal system. As a consequence, it leads to a decrease in the amount of salivary output and also affects the overall quality of life. The purpose of this study was to determine whether electrostimulation using a custom designed transcutaneous electrical nerve stimulation (TENS) device will help to improve the quality of secreted saliva following electrostimulation.

methodsOne hundred thirty-five participants underwent the intervention for three months, twice daily (80 Hz). Pre-intervention and post-intervention unstimulated saliva were collected. Parameters such as salivary pH, cortisol level, salivary antioxidants, total protein, the viscosity of saliva, and microbial carriage were analysed.

resultsSalivary pH, cortisol, microbial cultures, viscosity, and antioxidants showed a significant difference at the end of the 3rd month (p < 0.05). Irrespective of the patient's age, gender, and common underlying systemic illnesses (diabetes and hypertension), a significant change in the quality of the salivary analytes was observed.

conclusionThe study emphasises the use of a custom designed TENS device in improving the quality of secreted saliva among old patients with oral dryness.

Indexed as

Quality of LifeXerostomiaAgedAntioxidantsHumansHydrocortisoneSalivaAntioxidantsHydrocortisoneGeriatric patientsSalivaTENSUnstimulated salivaXerostomia

Identifiers

PMID37246232
PMCPMC10226253
OpenAlexW4378594060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.