Evidence map›Paper›PMID 37245694›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2023

Genome-wide analyses of gene expression profile identify key genes and pathways involved in skeletal response to phosphate and 1,25-dihydroxyvitamin D

Seong Min Lee, Mark B Meyer, Nancy A Benkusky, J Wesley Pike

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. TGFβ signaling regulates the response of the skeleton to phosphate.bioRxiv : the preprint server for biology · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Seong Min LeeDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: smlee4@wisc.edu.
Mark B MeyerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Nancy A BenkuskyDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
J Wesley PikeDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
University of Wisconsin–Madison · US

Funding

Integrative genomics to define osteocyte differentiation, regulation and functionR01AR064424 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2014 to 2018
$1.7M
Transcriptional Control of Mouse FGF23 Expression in Health and DiseaseR01DK118174 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI PIKE, J WESLEY · 2019 to 2021
$698k
NIAMS NIH HHS R01 AR064424NIDDK NIH HHS R01 DK118174
6 · The paper itself

Abstract

Phosphate (P) is an essential element involved in various biological actions, such as bone integrity, energy production, cell signaling and molecular component. P homeostasis is modulated by 4 main tissues; intestine, kidney, bone, and parathyroid gland, where 1,25-dihydroxyvitamin D

Indexed as

CalcitriolPhosphates24,25-Dihydroxyvitamin D 3AnimalsCalciumGenome-Wide Association StudyMiceTranscriptomeVitamin D1,25-dihydroxyvitamin D24,25-Dihydroxyvitamin D 3CalcitriolCalciumPhosphatesVitamin D1,25-dihydroxyvitamin D(3)BonePhosphateRNA-seqTranscriptionTranscriptomeWnt signaling pathway

Identifiers

PMID37245694
PMCPMC10527973
OpenAlexW4378364422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.