Evidence map›Paper›PMID 37245647›Full record

ArticleResuscitation2023

Hospital ECMO capability is associated with survival in pediatric cardiac arrest.

Blythe E Pollack, Ryan P Barbaro, Stephen M Gorga, Erin F Carlton, Michael Gaies, Joseph G Kohne

Abstract read
In one paragraph

Article in Resuscitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Extracorporeal membrane oxygenation (ECMO) in pediatric congenital heart disease: a comprehensive review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Blythe E PollackDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, United States. Electronic address: bpollack@med.umich.edu.
Ryan P BarbaroDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, United States; Susan B. Meister Child Health Evaluation and Research Center, University of Michigan School of Medicine, Ann Arbor, MI, United States.
Stephen M GorgaDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, United States.
Erin F CarltonDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, United States; Susan B. Meister Child Health Evaluation and Research Center, University of Michigan School of Medicine, Ann Arbor, MI, United States.
Michael GaiesDivision of Cardiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, United States.
Joseph G KohneDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, United States; Susan B. Meister Child Health Evaluation and Research Center, University of Michigan School of Medicine, Ann Arbor, MI, United States.

Funding

CTSA K12 Program at the University of MichiganK12TR004374 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI L ELLINGROD, Leah Elizabeth Robinson · 2023 to 2026
$6.5M
ASCEND (ARDS in Children and ECMO initiation strategies impact on Neuro-Development)R01HL153519 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BARBARO, RYAN PASQUALE · 2020 to 2024
$3.4M
Training to Advance Care Through Implementation Science in Cardiac And Lung Illnesses (TACTICAL)K12HL138039 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BARNES, GEOFFREY DOUGLAS, PRESCOTT, HALLIE CHRISTINE · 2017 to 2021
$3.1M
NCATS NIH HHS K12 TR004374NHLBI NIH HHS K12 HL138039NHLBI NIH HHS R01 HL153519
6 · The paper itself

Abstract

aimExtracorporeal membrane oxygenation (ECMO) provides temporary support in severe cardiac or respiratory failure and can be deployed in children who suffer cardiac arrest. However, it is unknown if a hospital's ECMO capability is associated with better outcomes in cardiac arrest. We evaluated the association between pediatric cardiac arrest survival and the availability of pediatric extracorporeal membrane oxygenation (ECMO) at the treating hospital.

methodsWe identified cardiac arrest hospitalizations, including in- and out-of-hospital, in children (0-18 years old) using data from the Health Care Utilization Project (HCUP) National Inpatient Sample (NIS) between 2016 and 2018. The primary outcome was in-hospital survival. Hierarchical logistic regression models were built to test the association between hospital ECMO capability and in-hospital survival.

resultsWe identified 1276 cardiac arrest hospitalizations. Survival of the cohort was 44%; 50% at ECMO-capable hospitals and 32% at non-ECMO hospitals. After adjusting for patient-level factors and hospital factors, receipt of care at an ECMO- capable hospital was associated with higher in-hospital survival, with an odds ratio of 1.49 [95% CI 1.09, 2.02]. Patients who received treatment at ECMO-capable hospitals were younger (median 3 years vs 11 years, p < 0.001) and more likely to have a complex chronic condition, specifically congenital heart disease. A total of 10.9% (88/811) of patients at ECMO-capable hospitals received ECMO support.

conclusionA hospital's ECMO capability was associated with higher in-hospital survival among children suffering cardiac arrest in this analysis of a large United States administrative dataset. Future work to understand care delivery differences and other organizational factors in pediatric cardiac arrest is necessary to improve outcomes.

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationHeart ArrestOut-of-Hospital Cardiac ArrestAdolescentChildChild, PreschoolHospitalsHumansInfantInfant, NewbornRetrospective StudiesTreatment OutcomeCardiac arrestCardiopulmonary resuscitation (CPR)Extracorporeal life support (ECLS)Extracorporeal membrane oxygenation (ECMO)Extracorporeal membrane oxygenation to support cardiopulmonary resuscitation (ECPR)Out of hospital cardiac arrest (OHCA)Pediatric

Identifiers

PMID37245647
PMCPMC10576981

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.