ArticleHealth and quality of life outcomes2023
Health-related quality of life among patients with knee osteoarthritis in Guangzhou, China: a multicenter cross-sectional study.
Article in Health and quality of life outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07224958 (ROAM OA), which is not on this map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA
Who cites it
11 citing papers in PubMed.
- Changes in health-related quality of life: a longitudinal registry study among over 15,000 participants of a digital education and exercise therapy for knee and hip osteoarthritis using EQ-5D-5L.Health and quality of life outcomes · 2026Article
- Quantitative refinement and multicentre psychometric validation of the Chinese total knee arthroplasty patient-reported outcome measure: a prospective cohort study with repeated measures.The Lancet regional health. Western Pacific · 2026Article
- Association between digestive diseases and symptomatic knee osteoarthritis in Chinese participants: a prospective cohort study.BMC public health · 2026Article
- Symptomatic knee osteoarthritis in older Thai adults: prevalence, risk factors, and associations with osteoporosis, sarcopenia, and fall risk-a nationwide cross-sectional study.BMC public health · 2026Article
- Multimodal model integrating ultrasound and demographic data for the diagnosis of knee osteoarthritis.BMC medical imaging · 2026Article
- Body Shape Indices and Chronic Knee Pain in Chinese Aging Population: A Longitudinal Analysis of Abdominal Obesity, BMI, and Waist Circumference.Journal of obesity · 2026Observational
- Functional Burden and Quality of Life in Hip and Knee Osteoarthritis: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- Platelet-rich plasma combined with isometric quadriceps contraction regulates autophagy in chondrocytes via the PI3K/AKT/mTOR pathway to promote cartilage repair in knee osteoarthritis.Regenerative therapy · 2025Article
- Mental health and health-related quality of life among adults with osteoarthritis: A national population-based study.PloS one · 2025Article
- Global, regional, and national burdens of osteoarthritis from 1990 to 2021: findings from the 2021 global burden of disease study.Frontiers in medicine · 2024Article
- Article
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Authors and funding
4 authors.
Funding
Abstract
purposesTo investigate health-related quality of life (HRQoL) of patients with knee osteoarthritis (KOA) in Guangzhou, China, and examine its association with selected sociodemographic characteristics as well as knee function.
methodsThis multicenter cross-sectional study included 519 patients with KOA in Guangzhou from April 1 to December 30, 2019. Data on sociodemographic characteristics were obtained using the General Information Questionnaire. The disability was measured using the KOOS-PS, resting pain using the Pain-VAS, and HRQoL using the EQ-5D-5L. The association of selected sociodemographic factors, KOOS-PS and Pain-VAS scores with HRQoL (EQ-5D-5L utility and EQ-VAS scores) were analyzed using linear regression analyses.
resultsThe median (interquartile range [IQR]) of EQ-5D-5L utility and EQ-VAS scores were 0.744 (0.571-0.841) and 70 (60-80) respectively, lower than the average HRQoL in the general population. Only 3.661% of KOA patients reported no problems in all EQ-5D-5L dimensions, with Pain/Discomfort being the most frequently affected dimension (78.805%). The correlation analysis showed that the KOOS-PS score, Pain-VAS score and HRQoL were moderately or strongly correlated. Patients with cardiovascular disease, no daily exercise, and high KOOS-PS or Pain-VAS scores had lower EQ-5D-5L utility scores; and patients with body mass index (BMI) > 28 ,high KOOS-PS or Pain-VAS scores had lower EQ-VAS scores.
conclusionsPatients with KOA had relatively low HRQoL. Various sociodemographic characteristics as well as knee function were associated with HRQoL in regression analyses. Providing social support and improving their knee function through methods such as total knee arthroplasty might be crucial to improve their HRQoL.
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