Evidence map›Paper›PMID 37244975›Full record

ArticleScientific reports2023

VEGF overexpressed mesoangioblasts enhance urethral and vaginal recovery following simulated vaginal birth in rats.

Marina G M C Mori da Cunha, Bernard K van der Veer, Giorgia Giacomazzi, Katerina Mackova, Laura Cattani, Kian Peng Koh, Greetje Vande Velde, Rik Gijsbers, Maarten Albersen, Maurilio Sampaolesi and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Marina G M C Mori da CunhaGroup Biomedical Sciences, Centre for Surgical Technologies, KU Leuven, Leuven, Belgium. biamori@gmail.com.
Bernard K van der VeerLaboratory for Stem Cell and Developmental Epigenetics, Department of Development and Regeneration, Stem Cell Institute Leuven, KU Leuven, Leuven, Belgium.
Giorgia GiacomazziTranslational Cardiomyology Laboratory, Stem Cell Biology and Embryology Unit, Department Development and Regeneration, Stem Cell Institute Leuven, KU Leuven, Leuven, Belgium.
Katerina MackovaGroup Biomedical Sciences, Centre for Surgical Technologies, KU Leuven, Leuven, Belgium.
Laura CattaniGroup Biomedical Sciences, Centre for Surgical Technologies, KU Leuven, Leuven, Belgium.
Kian Peng KohLaboratory for Stem Cell and Developmental Epigenetics, Department of Development and Regeneration, Stem Cell Institute Leuven, KU Leuven, Leuven, Belgium.
Greetje Vande VeldeDepartment of Imaging and Pathology, Biomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium.
Rik GijsbersLaboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Flanders, Belgium.
Maarten AlbersenDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Maurilio SampaolesiTranslational Cardiomyology Laboratory, Stem Cell Biology and Embryology Unit, Department Development and Regeneration, Stem Cell Institute Leuven, KU Leuven, Leuven, Belgium.
Jan DeprestGroup Biomedical Sciences, Centre for Surgical Technologies, KU Leuven, Leuven, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaginal birth causes pelvic floor injury which may lead to urinary incontinence. Cell therapy has been proposed to assist in functional recovery. We aim to assess if intra-arterial injection of rat mesoangioblasts (MABs) and stable Vascular Endothelial Growth Factor (VEGF)-expressing MABs, improve recovery of urethral and vaginal function following simulated vaginal delivery (SVD). Female rats (n = 86) were assigned to either injection of saline (control), allogeneic-MABs (MABs

Indexed as

UrethraUrinary Incontinence, StressAnimalsDisease Models, AnimalFemaleParturitionPregnancyRatsRats, Sprague-DawleyVascular Endothelial Growth Factor AVascular Endothelial Growth Factor A

Identifiers

PMID37244975
PMCPMC10224946
OpenAlexW4378531082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.