Evidence map›Paper›PMID 37244886›Full record

ArticleThe international journal of cardiovascular imaging2023

Myocardial work in children with Wolff-Parkinson-White syndrome.

Nunzia Borrelli, Giovanni Di Salvo, Giovanni Domenico Ciriello, Jolanda Sabatino, Martina Avesani, Isabella Leo, Rosaria Barracano, Giancarlo Scognamiglio, Maria Giovanna Russo, Berardo Sarubbi

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Article in The international journal of cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nunzia BorrelliAdult Congenital Heart Disease Unit, AO Dei Colli, Monaldi Hospital, Via Leonardo Bianchi, Naples, Italy. nunziaborrelli16@gmail.com.
Giovanni Di SalvoDivision of Paediatric Cardiology, Department of Women's and Children's Health, University Hospital of Padua, Padua, Italy.
Giovanni Domenico CirielloAdult Congenital Heart Disease Unit, AO Dei Colli, Monaldi Hospital, Via Leonardo Bianchi, Naples, Italy.
Jolanda SabatinoDivision of Paediatric Cardiology, Department of Women's and Children's Health, University Hospital of Padua, Padua, Italy.
Martina AvesaniDivision of Paediatric Cardiology, Department of Women's and Children's Health, University Hospital of Padua, Padua, Italy.
Isabella LeoDivision of Cardiology, Department of Medical and Surgical Science, Magna Graecia University, Catanzaro, Italy.
Rosaria BarracanoAdult Congenital Heart Disease Unit, AO Dei Colli, Monaldi Hospital, Via Leonardo Bianchi, Naples, Italy.
Giancarlo ScognamiglioAdult Congenital Heart Disease Unit, AO Dei Colli, Monaldi Hospital, Via Leonardo Bianchi, Naples, Italy.
Maria Giovanna RussoDivision of Paediatric Cardiology, University of Campania 'Luigi Vanvitelli', AO Dei Colli, Monaldi Hospital, Naples, Italy.
Berardo SarubbiAdult Congenital Heart Disease Unit, AO Dei Colli, Monaldi Hospital, Via Leonardo Bianchi, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wolff-Parkinson-White Syndrome (WPW) has been associated with reduced local myocardial deformation, and when left ventricular dysfunction is present, catheter ablation of the accessory pathway may be required, even in asymptomatic patients. We aimed to evaluate the diagnostic value of non-invasive myocardial work in predicting subtle abnormalities in myocardial performance in children with WPW.Seventy-five paediatric patients (age 8.7 ± 3.5 years) were retrospectively recruited for the study: 25 cases with manifest WPW and 50 age- and sex- matched controls (CTR). Global myocardial work index (MWI) was measured as the area of the left ventricle (LV) pressure-strain loops. From MWI, global Myocardial Constructive Work (MCW), Wasted Work (MWW), and Work Efficiency (MWE) were estimated. In addition, standard echocardiographic parameters of LV function were evaluated. Despite normal LV ejection fraction (EF) and global longitudinal strain (GLS), children with WPW had worse MWI, MCW, MWW, and MWE. At multivariate analysis, MWI and MCW were associated with GLS and systolic blood pressure, and QRS was the best independent predictor of low MWE and MWW. In particular, a QRS > 110 ms showed good sensitivity and specificity for worse MWE and MWW values. In children with WPW, myocardial work indices were found significantly reduced, even in the presence of normal LV EF and GLS. This study supports the systematic use of myocardial work during the follow-up of paediatric patients with WPW. Myocardial work analysis may represent a sensitive measure of LV performance and aid in decision-making.

Indexed as

Wolff-Parkinson-White SyndromeChildChild, PreschoolEchocardiographyHumansMyocardiumPredictive Value of TestsRetrospective StudiesStroke VolumeVentricular Function, LeftAccessory pathwayChildrenGlobal longitudinal strainNon-invasive myocardial workWolf-Parkinson-White Syndrome

Identifiers

PMID37244886

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.