Evidence map›Paper›PMID 37244842›Full record

ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2024

Quantifying variation in home spirometry in people with cystic fibrosis during baseline health, and associations with clinical outcomes.

Christina S Thornton, Amalia S Magaret, Lisa A Carmody, Linda M Kalikin, Richard H Simon, John J LiPuma, Lindsay J Caverly

Open access · greenAbstract read
In one paragraph

Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Cystic fibrosis year in review 2023.Pediatric pulmonology · 2024
    Review
  5. Baseline-dependent improvement in CF studies, plausibility of bias.Contemporary clinical trials communications · 2024
    Article
  6. Impact of day-to-day variation in FEV1 on measures of change: A conceptual description.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2024
    Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christina S ThorntonDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Amalia S MagaretDepartments of Pediatrics and Biostatistics, University of Washington, Seattle, Washington, USA.
Lisa A CarmodyDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Linda M KalikinDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Richard H SimonDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
John J LiPumaDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Lindsay J CaverlyDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA. Electronic address: caverlyl@med.umich.edu.
University of Michigan · USUniversity of Washington · US

Funding

Dynamics of airway microbiota at pulmonary exacerbation in cystic fibrosisR01HL136647 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIPUMA, JOHN J · 2017 to 2020
$1.3M
NHLBI NIH HHS R01 HL136647
6 · The paper itself

Abstract

backgroundHome spirometry is increasingly used to monitor lung function in people with cystic fibrosis (pwCF). Although decreases in lung function in the setting of increased respiratory symptoms are consistent with a pulmonary exacerbation (PEx), the interpretation of home spirometry during asymptomatic periods of baseline health is unclear. The aims of this study were to determine the variation in home spirometry in pwCF during asymptomatic periods of baseline health and to identify associations between this variation and PEx.

methodsNear-daily home spirometry measurements were obtained from a cohort of pwCF enrolled in a long-term study of the airway microbiome. Associations between the degree of variation in home spirometry and the time to next PEx were evaluated.

resultsThirteen subjects (mean age of 29 years and mean percent predicted forced expiratory volume in one second [ppFEV

conclusionsVariation in ppFEV

Indexed as

Cystic FibrosisSpirometryAdultDisease ProgressionFemaleForced Expiratory VolumeHumansMaleBaseline healthCystic fibrosisExacerbationHome spirometryLung function

Identifiers

PMID37244842
PMCPMC10674030
OpenAlexW4378417450

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.