Evidence map›Paper›PMID 37243975›Full record

ArticlePediatric blood & cancer2023

Prognostic value of chest x-ray- and CT-defined large mediastinal adenopathy in high-risk pediatric Hodgkin lymphoma: A report from the Children's Oncology Group Study AHOD0831.

Andrea C Lo, Inki Lee, Qinglin Pei, Yue Wu, Kathleen M McCarten, Bradford S Hoppe, David C Hodgson, Kenneth Roberts, Sarah Milgrom, Sandy Kessel and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric blood & cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 3 countries.

Andrea C LoDepartment of Radiation Oncology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.ORCID 0000-0002-3253-1071
Inki LeeDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Qinglin PeiChildren's Oncology Group, Statistics and Data Center, Monrovia, California, USA.
Yue WuChildren's Oncology Group, Statistics and Data Center, Monrovia, California, USA.
Kathleen M McCartenImaging and Radiation Oncology Core, Lincoln, Rhode Island, USA.
Bradford S HoppeDepartment of Radiation Oncology, Mayo Clinic Florida, Rochester, Florida, USA.ORCID 0000-0002-2312-5418
David C HodgsonRadiation Oncology, Princess Margaret Cancer Center and University of Toronto, Toronto, Ontario, Canada.
Kenneth RobertsDepartment of Radiation Oncology, Yale University School of Medicine, New Haven, Connecticut, USA.
Sarah MilgromDepartment of Radiation Oncology, University of Colorado, Aurora, Colorado, USA.ORCID 0000-0003-0037-6967
Sandy KesselImaging and Radiation Oncology Core, Lincoln, Rhode Island, USA.
Peter D ColeRutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.ORCID 0000-0002-3525-8015
Kara M KellyPediatric Hematology/Oncology, Roswell Park Comprehensive Cancer Center, University at Buffalo, Buffalo, New York, USA.
Steve Y ChoDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
University of Florida · USUniversity of Wisconsin–Madison · USBC Cancer Agency · CAMayo Clinic in Florida · USRoswell Park Comprehensive Cancer Center · USRutgers, The State University of New Jersey · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Toronto · CAYale University · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

PURPOSE/

objectiveWe compared the prognostic value of chest radiograph (CXR)- and computed tomography (CT)-derived definition of large mediastinal adenopathy (LMA) in pediatric Hodgkin lymphoma (HL). MATERIALS/

methodsTotal 143 patients treated for stage IIIB/IVB HL on COG AHOD0831 were included in this study. Six definitions of LMA were investigated: (i) mediastinal mass ratio on CXR (MR

resultsMedian age at diagnosis was 15.8 years (range: 5.2-21.3 years). In patients with a slow early response (SER) to chemotherapy, MV

conclusionLMA according to MV

Indexed as

Hodgkin DiseaseLymphadenopathyAdolescentAdultAntineoplastic Combined Chemotherapy ProtocolsChildChild, PreschoolHumansNeoplasm Recurrence, LocalPrognosisTomography, X-Ray ComputedX-RaysYoung AdultHodgkin's diseaselymphomapediatric hematology/oncology

Identifiers

PMID37243975
PMCPMC10546608
OpenAlexW4378530625

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.