Evidence map›Paper›PMID 37243943›Full record

Trial reportCancer2023

The feasibility, acceptability, and preliminary efficacy of a self-advocacy serious game for women with advanced breast or gynecologic cancer.

Teresa Hagan Thomas, Catherine Bender, Heidi S Donovan, Patty Jo Murray, Sarah Taylor, Margaret Rosenzweig, Susan M Sereika, Adam Brufsky, Yael Schenker

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Teresa Hagan ThomasSchool of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7403-7314
Catherine BenderSchool of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Heidi S DonovanSchool of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Patty Jo MurraySchool of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sarah TaylorUniversity of Pittsburgh Medical Center Magee-Womens Hospital, Pittsburgh, Pennsylvania, USA.
Margaret RosenzweigSchool of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Susan M SereikaSchool of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Adam BrufskyUniversity of Pittsburgh Medical Center Magee-Womens Hospital, Pittsburgh, Pennsylvania, USA.
Yael SchenkerPalliative Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Extension of STRONG Study to Expand Intervention ImpactR37CA262025 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Teresa Hagan Thomas · 2021 to 2026
$3.7M
Midcareer Investigator Award in Patient-Oriented Research: Yael Schenker, MD, MASK24AG070285 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHENKER, YAEL · 2021 to 2025
$841k
NCI NIH HHS P30 CA047904NCI NIH HHS R37 CA262025NIA NIH HHS K24 AG070285
6 · The paper itself

Abstract

backgroundCancer clinicians and systems aim to provide patient-centered care, but not all patients have the self-advocacy skills necessary to ensure their care reflects their needs and priorities. This study examines the feasibility, acceptability, and preliminary efficacy of a self-advocacy serious game (an educational video game) intervention in women with advanced breast or gynecologic cancer.

methodsWomen with recently diagnosed (<3 months) metastatic breast or advanced gynecologic cancer were randomized 2:1 to receive a tablet-based serious game (Strong Together) (n = 52) or enhanced care as usual (n = 26). Feasibility was based on recruitment, retention, data completion, and intervention engagement. Acceptability was assessed via a postintervention questionnaire and exit interview. Preliminary efficacy was assessed on the basis of change scores from baseline to 3 and 6 months in self-advocacy (Female Self-Advocacy in Cancer Survivorship Scale) using intention-to-treat analysis.

resultsSeventy-eight women (55.1% with breast cancer; 44.9% with gynecologic cancer) were enrolled. Feasibility was demonstrated by satisfactory recruitment (69% approach-to-consent rate; 93% enroll-to-randomize rate), retention (90% and 86% at 3 and 6 months, respectively; 85% data completion), and intervention engagement (84% completed ≥75% of the game). Participants endorsed the intervention's (75%) and trial's (87%) acceptability. Participants in the intervention group experienced significant improvements in self-advocacy at 3 and 6 months compared to participants in the control group.

conclusionsStrong Together is feasible and acceptable among women with advanced breast or gynecologic cancer. This intervention demonstrates promising evidence of clinical efficacy. A future confirmatory trial is warranted to test the efficacy of the intervention for patient and health system outcomes.

Indexed as

Breast NeoplasmsGenital Neoplasms, FemaleFeasibility StudiesFemaleHumansSurveys and QuestionnairesTreatment Outcomebreast cancergynecologic cancermobile applicationspatient-centered careself-advocacyself-management

Identifiers

PMID37243943
PMCPMC12105837
OpenAlexW4378530490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.