Evidence map›Paper›PMID 37243938›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2023

Value of frontal QRS axis for risk stratification of individuals with prolonged PR interval.

Xiaodi Cao, Zhe Wang, Zhang Fang, Chuanchuan Yu, Linsheng Shi

Open access · goldAbstract read
In one paragraph

Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Determining the QRS axis: visual estimation is equal to calculation.Herzschrittmachertherapie & Elektrophysiologie · 2025
    Article
  2. Value of frontal QRS axis for risk stratification of individuals with prolonged PR interval.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Xiaodi CaoDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-6872-5671
Zhe WangDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-9238-4088
Zhang FangDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-6185-3187
Chuanchuan YuDepartment of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0003-3450-9457
Linsheng ShiDepartment of Cardiology, The Second Affiliated Hospital of Nantong University, Nantong, China.ORCID 0000-0002-7763-5368
Jiangsu Province Hospital · CNNantong University · CNSun Yat-sen University · CN

Funding

Grant of Jiangsu Commission of Health LKM2022060Grant of Nantong Commission of Health MA2021013Research innovation team project from Kangda college of Nanjing Medical School KD2022KYCXTD009Science Foundation of Nantong City JC2021139
6 · The paper itself

Abstract

backgroundThere is ongoing controversy regarding the prognostic value of PR prolongation among individuals free of cardiovascular diseases. It is necessary to risk-stratify this population according to other electrocardiographic parameters.

methodsThis study is based on the Third National Health and Nutrition Examination Survey. Cox proportional hazard models were constructed and Kaplan-Meier method was used.

resultsA total of 6188 participants (58.1 ± 13.1 years; 55% women) were included. The median frontal QRS axis of the entire study population was 37° (IQR: 11-60°). PR prolongation was present in 7.6% of the participants, of whom 61.2% had QRS axis ≤37°. In a multivariable-adjusted model, mortality risk was highest in the group with concomitant prolonged PR interval and QRS axis ≤37° (hazard ratio [HR]: 1.20; 95% confidence interval [CI]: 1.04-1.39). In models with similar adjustment where population were reclassified depending on PR prolongation and QRS axis, prolonged PR interval and QRS axis ≤37° was still associated with increased risk of mortality (HR: 1.18; 95% CI: 1.03-1.36) compared with normal PR interval.

conclusionsQRS axis is an important factor for risk stratification in population with PR prolongation. The extent to which this population with PR prolongation and QRS axis ≤37° is at higher risk of death compared with the population without PR prolongation.

Indexed as

Atrioventricular BlockElectrocardiographyFemaleHumansMaleNutrition SurveysRisk AssessmentRisk Factorselectrocardiogram indicatorsPR intervalQRS axisrisk stratification

Identifiers

PMID37243938
PMCPMC10335622
OpenAlexW4378530019

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.