Evidence map›Paper›PMID 37243879›Full record

ArticleBiological trace element research2024

The Role of Thyroid Hormone Synthesis Gene-Related miRNAs Profiling in Structural and Functional Changes of The Thyroid Gland Induced by Excess Iodine.

Chunyu Zhang, Jinyin Yao, Chang Liu, Kunying Yang, Wei Zhang, Dianjun Sun, Weikuan Gu

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Unique miRomics Expression Profiles inInternational journal of molecular sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chunyu ZhangCenter for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province &, Heilongjiang Provincial Key Laboratory of Trace Elements and Human Health, Ministry of Health, 157# Baojian Road Harbin, 150081, Harbin, China.
Jinyin YaoDepartment of Public Health, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China.
Chang LiuCenter for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province &, Heilongjiang Provincial Key Laboratory of Trace Elements and Human Health, Ministry of Health, 157# Baojian Road Harbin, 150081, Harbin, China.
Kunying YangCenter for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province &, Heilongjiang Provincial Key Laboratory of Trace Elements and Human Health, Ministry of Health, 157# Baojian Road Harbin, 150081, Harbin, China.
Wei ZhangCenter for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province &, Heilongjiang Provincial Key Laboratory of Trace Elements and Human Health, Ministry of Health, 157# Baojian Road Harbin, 150081, Harbin, China. zwhxd@126.com.
Dianjun SunCenter for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Key Lab of Etiology and Epidemiology, Education Bureau of Heilongjiang Province &, Heilongjiang Provincial Key Laboratory of Trace Elements and Human Health, Ministry of Health, 157# Baojian Road Harbin, 150081, Harbin, China. hrbmusdj@163.com.
Weikuan GuDepartment of Orthopedic Surgery and BME-Campbell Clinic, University of Tennessee Health Science Center, Memphis, TN, 38163, USA. wgu@uthsc.edu.
Harbin Medical University · CNShandong Provincial Hospital · CNUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At recent years, the impairment caused by iodine excess are paid more attention. However, there is still largely unknown about the exact mechanism induced by excessive iodine. MiRNAs have been found to act as biomarkers for a variety of diseases, whereas fewer studies focused on miRNAs related to a cluster of genes regulating thyroid hormone synthesis, such as NIS, Pendrin, TPO, MCT8, TSHR, TSHα, and TSHβ-related miRNAs in structural and functional changes of the thyroid gland induced by subchronic and chronic high iodine exposure. In the present study, one hundred and twenty 4-week-old female Wistar rats were randomly divided into control group (I

Indexed as

HypothyroidismIodineMicroRNAsAnimalsFemaleRatsRats, WistarRNA, MessengerThyroid HormonesIodineMicroRNAsMIRN185 microRNA, ratMIRN24 microRNA, ratRNA, MessengerThyroid HormonesGoiterHypothyroidismIodine excessmiRNASubclinical hypothyroidism

Identifiers

PMID37243879
OpenAlexW4378530155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.