Evidence map›Paper›PMID 37243797›Full record

ArticleApplied health economics and health policy2023

Symptomatic SARS-CoV-2 Episodes and Health-Related Quality of Life.

Caterina Alacevich, Inna Thalmann, Catia Nicodemo, Simon de Lusignan, Stavros Petrou

Open access · bronzeAbstract read
In one paragraph

Article in Applied health economics and health policy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Caterina AlacevichNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK. calacevich@ufl.edu.ORCID http://orcid.org/0000-0003-3931-3103
Inna ThalmannNuffield Department of Population Health, University of Oxford, Oxford, UK.
Catia NicodemoNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Simon de LusignanNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Stavros PetrouNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
University of Oxford · GBUniversity of Florida Health · USUniversity of Verona · IT

Funding

Economic and Social Research Council ES/T008415/1NIHR Senior Investigator NF-SI-0616-10103
6 · The paper itself

Abstract

backgroundUnderstanding the physical and mental health needs of the population through evidence-based research is a priority for informing health policy. During the COVID-19 pandemic, population wellbeing dramatically dropped. The relationship between experiences of symptomatic illness episodes and health-related quality of life has been less documented.

objectiveThis study analysed the association between symptomatic COVID-19 illness and health-related quality of life.

methodsThe analyses drew from a cross-sectional analysis of data from a national digital symptoms' surveillance survey conducted in the UK in 2020. We identified illness episodes using symptoms and test results data and we analysed validated health-related quality of life outcomes including health utility scores (indexed on a 0-1 cardinal scale) and visual analogue scale (VAS) scores (0-100 scale) generated by the EuroQoL's EQ-5D-5L measure. The econometric model controlled for respondents' demographic and socioeconomic characteristics, comorbidities, social isolation measures, and regional and time fixed effects.

resultsThe results showed that the experience of common SARS-CoV-2 symptoms was significantly associated with poorer health-related quality of life across all EQ-5D-5L dimensions of mobility, self-care, usual activities, pain/discomfort and anxiety/depression, a decrement in utility score of - 0.13 and a decrement in the EQ-VAS score of - 15. The findings were robust to sensitivity analyses and restrictive test results-based definitions.

conclusionThis evidence-based study highlights the need for targeting of interventions and services towards those experiencing symptomatic episodes during future waves of the pandemic and helps to quantify the benefits of SARS-CoV-2 treatment in terms of health-related quality of life.

Indexed as

COVID-19Quality of LifeCross-Sectional StudiesHealth StatusHumansPandemicsSARS-CoV-2Surveys and Questionnaires

Identifiers

PMID37243797
PMCPMC10224647
OpenAlexW4378549297

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.