ArticleInternational journal of bipolar disorders2023
Clinicians' preferences and attitudes towards the use of lithium in the maintenance treatment of bipolar disorders around the world: a survey from the ISBD Lithium task force.
Article in International journal of bipolar disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Persistence of Lithium Underutilization in Patients of African Ancestry with Bipolar Disorder.Psychopharmacology bulletin · 2025Pooled it
- Cortical morphometry might predict currently prescribed vs. discontinued medications in bipolar disorder, even after controlling for the cumulative dose effects: An ENIGMA mega-analysis.Molecular psychiatry · 2026Article
- Time to lithium: A case register study of lithium initiation in bipolar disorder.Journal of psychopharmacology (Oxford, England) · 2026Article
- Lithium prescribing in the perinatal period: UK primary care cohort study.The British journal of psychiatry : the journal of mental science · 2026Article
- Could Lithium Be Preserved for the Stabilization of Bipolar Patients?Pharmaceuticals (Basel, Switzerland) · 2026Review
- Article
- Lithium prescription patterns for bipolar disorder at a psychiatric hospital in KwaZulu-Natal.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026Article
- A qualitative exploration of perspectives on taking lithium supplements.Therapeutic advances in psychopharmacology · 2026Article
- Lithium Point-of-Care Testing to Improve Adherence to Monitoring Guidelines and Quality of Maintenance Therapy: Protocol for a Randomised Feasibility Trial.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Analysing lithium, quetiapine and valproic acid on social media: an infodemiology study.International journal of bipolar disorders · 2025Article
- A Survey Exploring People's Experiences With Lithium Bought as a Supplement: Une enquête sur l'expérience des personnes avec le lithium en supplément.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2025Article
- Sex differences in lithium concentrations among bipolar patients with different episodes based on real-world therapeutic monitoring data.BMC psychiatry · 2025Observational
- Prescribing lithium for the management of persons suffering from bipolar disorders: expert consensus based on a Delphi study.International journal of bipolar disorders · 2025Article
- Challenges of lithium prescription in bipolar disorders in Nigeria.BMC psychiatry · 2025Article
- Understanding social media discourse on antidepressants: unsupervised and sentiment analysis using X.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Twenty-four years of prescription patterns in bipolar disorder inpatients with vs without lithium: a pharmacoepidemiological analysis of 8,707 cases in German-speaking countries.International journal of bipolar disorders · 2025Article
- Comprehensive bibliometric analysis of pharmacotherapy for bipolar disorders: Present trends and future directions.World journal of psychiatry · 2025Article
- Lithium in Drinking Water and its Potential Impact on Mental Health: A Review.Current medicinal chemistry · 2025Review
- Attitudes toward lithium prescription among psychiatrists in Saudi Arabia: a cross-sectional study.Frontiers in psychiatry · 2025Article
- Underlying biological mechanisms of emotion dysregulation in bipolar disorder.Frontiers in psychiatry · 2025Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLithium has long been considered the gold-standard pharmacological treatment for the maintenance treatment of bipolar disorders (BD) which is supported by a wide body of evidence. Prior research has shown a steady decline in lithium prescriptions during the last two decades. We aim to identify potential factors explaining this decline across the world with an anonymous worldwide survey developed by the International Society for Bipolar Disorders (ISBD) Task Force "Role of Lithium in Bipolar Disorders" and distributed by diverse academic and professional international channels.
resultsA total of 886 responses were received of which 606 completed the entire questionnaire while 206 completed it partially. Respondents were from 43 different countries comprising all continents. Lithium was the most preferred treatment option for the maintenance of BD patients (59%). The most relevant clinical circumstances in which lithium was the preferred option were in patients with BD I (53%), a family history of response (18%), and a prior response during acute treatment (17%). In contrast, Lithium was not the preferred option in case of patients´ negative beliefs and/or attitudes towards lithium (13%), acute side-effects or tolerability problems (10%) and intoxication risk (8%). Clinicians were less likely to prefer lithium as a first option in BD maintenance phase when practising in developing economy countries [X2 (1, N = 430) = 9465, p = 0.002) ] and private sectors [X2 (1, N = 434) = 8191, p = 0.004)].
conclusionsClinicians' preferences and attitudes towards the use of lithium in the maintenance treatment of bipolar disorders appear to be affected by both the patients' beliefs and the professional contexts where clinicians provide their services. More research involving patients is needed for identifying their attitudes toward lithium and factors affecting its use, particularly in developing economies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.